Nerve Transfer for Finger Sensory Reconstruction With Dorsal Branch of the Digital Nerve

NCT01559337 | Completed DMC

• 1 other identifier: CHEN-19750471
• Study Type: interventional
• Target: 17
• Locations: 1 country
• Sites: 1

Brief Summary

A proper digital nerve (PDN) defect causes partial or complete sensory loss of the finger pulp, which results in functional disability.The dorsal branch of the PDN can be transferred for reconstruction of such nerve defects.In this study, the investigators modified the Lesavoy et al' technique and evaluated the efficacy of dorsal sensory branch transfer for PDN defects. For comparison, the investigators collected a consecutive series of 32 patients with finger PDN defects treated using a traditional sural nerve graft from February 2005 to October 2008.

Conditions

Sensory Restoration of the Reconstructed Finger Pulps; Cold Intolerance of the Reconstructed Finger; Pain of the Reconstructed Finger

Keywords

defect; dorsal branch of the proper digital nerve; proper digital nerve; nerve transfer; finger sensory reconstruction

Outcome Measures

Primary Outcomes (1)

• static 2-point discrimination (2PD) test

  At final follow-up, we measured the sensibility of the pulps and the donor sites using the static 2-point discrimination (2PD) test. The test points were at the center of the radial or ulnar portion of the pulp and the donor sites separately. Each area was tested 3 times with a Dellon-Mackinnon discriminator. Two out of 3 correct answers were considered proof of perception before proceeding to another lower value.

  26 months

Secondary Outcomes (1)

• self-administered Cold Intolerance Severity Score (CISS) questionnaire

  26 months

Study Arms (1)

Nerve repair

OTHER

the dorsal branch of the proper digital nerve was used as a pedicle nerve for reconstructing PDN defects

Procedure: Nerve transfer

Interventions

Nerve transfer PROCEDURE

the dorsal branch was used as a pedicle nerve for reconstructing PDN defects

Also known as: Local pedicle nerve transfer

Nerve repair

Eligibility Criteria

• Age: 15 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Finger PDN defects proximal to the proximal interphalangeal joint
• Single or two PDN defects
• PDN defects longer than 1 cm.

You may not qualify if:

• PDN defects less than 1 cm
• Concomitant injuries to the multiple dorsal sensory branches that preclude their use as nerve donor sites
• Thumb PDN defects.

Sponsors & Collaborators

• The Second Hospital of Tangshan: lead

Study Sites (1)

Ethetic Committee of Tangshan

Tangshan, Hebei, 063000, China

Location

MeSH Terms

Interventions

Nerve Transfer

Intervention Hierarchy (Ancestors)

Neurosurgical Procedures; Surgical Procedures, Operative

Study Officials

• Peifu Tang, MD.

  Chinese PLA General Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 19, 2012
• First Posted: March 21, 2012
• Study Start: May 1, 2007
• Primary Completion: June 1, 2009
• Study Completion: January 1, 2012
• Last Updated: March 21, 2012

Record last verified: 2012-03

Locations

CN (1)