NCT01558479

Brief Summary

The Parkinson's Genetic Research Study (PaGeR), headed by Dr. Cyrus Zabetian, is searching for genes that increase the risk of developing Parkinson's disease (PD) and related disorders. The study is a joint effort by neurologists and researchers across the United States and is sponsored by the National Institutes of Health. The coordinating center for PaGeR is located at the University of Washington and the VA Puget Sound Health Care System in Seattle.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,000

participants targeted

Target at P75+ for all trials

Timeline
6mo left

Started Sep 2009

Longer than P75 for all trials

Geographic Reach
1 country

5 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress97%
Sep 2009Oct 2026

Study Start

First participant enrolled

September 1, 2009

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

March 16, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 20, 2012

Completed
14.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2026

Last Updated

May 14, 2024

Status Verified

May 1, 2024

Enrollment Period

17.2 years

First QC Date

March 16, 2012

Last Update Submit

May 11, 2024

Conditions

Keywords

Parkinson's DiseaseGeneticsFamily ResearchHereditary Neurodegenerative Diseases

Study Arms (3)

Case

Has a diagnosis of Parkinson's disease

Control

No diagnosis of Parkinson's disease

Family Member

Has a family history of Parkinson's disease. Can be affected or unaffected with Parkinson's disease

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Families in which two or more people have been diagnosed with Parkinson's disease.

You may qualify if:

  • Over 18 years of age
  • Member of a family in which there are two or more living individuals who have been diagnosed with Parkinson's disease

You may not qualify if:

  • Under 18 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Emory University/ Wesley Woods Health Center

Atlanta, Georgia, 30329, United States

RECRUITING

University of Cincinnati

Cincinnati, Ohio, 45267, United States

RECRUITING

Portland VA Medical Center

Portland, Oregon, 97239, United States

RECRUITING

VA Puget Sound Health Care System

Seattle, Washington, 98108, United States

RECRUITING

University of Washington

Seattle, Washington, 98118, United States

RECRUITING

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

Blood or saliva

MeSH Terms

Conditions

Parkinson DiseaseHeredodegenerative Disorders, Nervous System

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Cyrus Zabetian, MD, MS

    University of Washington, VA Puget Sound Health Care System

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jennifer Pate

CONTACT

Khryss Capawa

CONTACT

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Neurology

Study Record Dates

First Submitted

March 16, 2012

First Posted

March 20, 2012

Study Start

September 1, 2009

Primary Completion (Estimated)

October 31, 2026

Study Completion (Estimated)

October 31, 2026

Last Updated

May 14, 2024

Record last verified: 2024-05

Locations