NCT01551563

Brief Summary

The study aims at studying the outcomes of a protocol-based handling of newly diagnosed Inflammatory bowel disease ( IBD ) patients within a defined uptake area in Norway. It is a descriptive study and no hypothesis is predefined. Cytokine studies, QoL and fatigue assessment will be included for hypothesis-generating purposes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
700

participants targeted

Target at P75+ for all trials

Timeline
52mo left

Started Apr 2012

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress77%
Apr 2012Dec 2030

First Submitted

Initial submission to the registry

March 8, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 12, 2012

Completed
20 days until next milestone

Study Start

First participant enrolled

April 1, 2012

Completed
14.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2030

Last Updated

May 16, 2025

Status Verified

May 1, 2025

Enrollment Period

14.7 years

First QC Date

March 8, 2012

Last Update Submit

May 13, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Clinical efficacy of IBD drug therapy

    Endoscopic, clinical and biochemical response

    5 years

Secondary Outcomes (3)

  • Fatigue in patients with coeliac disease - substudy

    1 year

  • Fatigue in IBD

    5 years

  • IBD and the intestinal microbiome

    5 years

Eligibility Criteria

Age16 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All newly diagnosed IBD patients (Crohns and Ulcerative colitis) within Stavanger Univ Hospital catchment area

You may qualify if:

  • newly diagnosed IBD

You may not qualify if:

  • previous IBD with specific treatment within 10 year
  • inability to consent
  • inability to adhere to treatment protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SUS

Stavanger, Norway

RECRUITING

Related Publications (3)

  • Skjellerudsveen BM, Omdal R, Hetta AK, Kvaloy JT, Aabakken L, Skoie IM, Grimstad T. Less, but not gone-gluten-free diet effects on fatigue in celiac disease: a prospective controlled study. Front Med (Lausanne). 2023 Sep 12;10:1242512. doi: 10.3389/fmed.2023.1242512. eCollection 2023.

  • Grimstad T, Skoie IM, Doerner J, Isaksen K, Karlsen L, Aabakken L, Omdal R, Putterman C. TWEAK is not elevated in patients with newly diagnosed inflammatory bowel disease. Scand J Gastroenterol. 2017 Apr;52(4):420-424. doi: 10.1080/00365521.2016.1273382. Epub 2016 Dec 31.

  • Grimstad T, Norheim KB, Isaksen K, Leitao K, Hetta AK, Carlsen A, Karlsen LN, Skoie IM, Goransson L, Harboe E, Aabakken L, Omdal R. Fatigue in Newly Diagnosed Inflammatory Bowel Disease. J Crohns Colitis. 2015 Sep;9(9):725-30. doi: 10.1093/ecco-jcc/jjv091. Epub 2015 May 19.

Biospecimen

Retention: SAMPLES WITH DNA

Plasma and mucosal biopsies Fecal sampling

Study Officials

  • Tore Grimstad, PhD

    Helse Stavanger HF

    PRINCIPAL INVESTIGATOR

Central Study Contacts

tore grimstad

CONTACT

lars aabakken

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 8, 2012

First Posted

March 12, 2012

Study Start

April 1, 2012

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2030

Last Updated

May 16, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations