Airway Involvement In Inflammatory Bowel Disease
Spectrum Of Airway Involvement In Inflammatory Bowel Disease
1 other identifier
observational
70
0 countries
N/A
Brief Summary
To estimate prevalence of subclinical airway injuries among IBD patients. To investigate relationship between activity of IBD and airways
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Nov 2023
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 13, 2023
CompletedFirst Posted
Study publicly available on registry
October 19, 2023
CompletedStudy Start
First participant enrolled
November 20, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 20, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 25, 2024
CompletedOctober 19, 2023
October 1, 2023
1 year
October 13, 2023
October 13, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Predictors of airway diseases in patients with IBD
FROM risk factors
baseline
Secondary Outcomes (1)
-Prevalence of of subclinical airway injuries among IBD patients presented to Tropical Department in Assiut University Hospital
baseline
Eligibility Criteria
After taking the informed consent, full history will be taken from all patients participating in the study. Detailed clinical examination and routine laboratory investigations (complete blood count, liver function test, urea, creatinine and ESR) will be done Clinical notes will be obtain and review for all patients with a diagnosis of IBD (history of bowel surgery (for IBD, or indication not stated), use of 5-aminosalicylates or immunomodulators (if indication not stated) ). Diagnosis of IBD will confirm on the basis of a consistent clinical picture with endoscopic and histological confirmation, or characteristic radiological appearances. Airways disease will classify on the following grounds: asthma,.COPD:,Bronchiectasis,.Chronic bronchitis:
You may qualify if:
- Patients attended to IBD clinic at Tropical Department
You may not qualify if:
- Age: less than 18 years
- Unstable patients or need for ICU admission
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Vutcovici M, Brassard P, Bitton A. Inflammatory bowel disease and airway diseases. World J Gastroenterol. 2016 Sep 14;22(34):7735-41. doi: 10.3748/wjg.v22.i34.7735.
PMID: 27678355BACKGROUNDByrd KM, Gulati AS. The "Gum-Gut" Axis in Inflammatory Bowel Diseases: A Hypothesis-Driven Review of Associations and Advances. Front Immunol. 2021 Feb 19;12:620124. doi: 10.3389/fimmu.2021.620124. eCollection 2021.
PMID: 33679761BACKGROUND
Study Officials
- STUDY CHAIR
Marwa Salama, MD
Assiut University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecture
Study Record Dates
First Submitted
October 13, 2023
First Posted
October 19, 2023
Study Start
November 20, 2023
Primary Completion
November 20, 2024
Study Completion
December 25, 2024
Last Updated
October 19, 2023
Record last verified: 2023-10