Sponsor study identifier
observational
1
1 country
1
Study Start
January 2012
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2015
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Study Completion
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Cultivated oral mucosal epithelial sheets on amniotic membrane have been reported to have good clinical results in treating patients with ocular surface disorders in both human and animal studies. However, such technique has not been well established in this hospital. The main purpose of this study is to obtain the discarded oral mucosal tissue from healthy donors who volunteer to donate their oral mucosa from buccal area. The obtained oral mucosal tissue will be cultured under different types (co-culture with or without 3T3 cells)。Inverted light microscopy, electron microscopy and immunostaining with K3/K12, K14, Ki67, P63, connexin 43, and involucrin will be preformed to test the effects of foreskin cell line co-culture system on cell condition. The investigators plan to start the study from Jan. 1st, 2011 to Dec. 31th, 2015. Thirty patients will be enrolled.
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December 2015
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January 2012
Date type not reportedThis date has not been verified as actual or estimated.
March 5, 2012
Actual (reported)March 8, 2012
Actual (reported)December 2015
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December 2015
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Donating oral mucosal cells
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Health people.
National Taiwan University Hospital, department of Ophthalmology
Taipei, 100, Taiwan
Donating oral mucosal cells for the study of ex vivo culture of cells sheets.
First Submitted
March 5, 2012
First Posted
March 8, 2012
Study Start
January 2012
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2015
Sublingual Microcirculation of Healthy Volunteers by Using the Third Generation Microcirculation Video Microscope
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
March 8, 2012
Record last verified: 2012-03
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Source: ClinicalTrials.gov.
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