NCT01547468

Brief Summary

The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for pain control. Post-operative delirium is confusion that can happen after the deep sleep of anesthesia. AThe hypothesis is that the group receiving the femoral nerve catheter for pain may have a lower incidence of delirium than the group receiveing IV pain medication.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Mar 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 27, 2012

Completed
3 days until next milestone

Study Start

First participant enrolled

March 1, 2012

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 7, 2012

Completed
10.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 19, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 19, 2022

Completed
Last Updated

April 27, 2022

Status Verified

April 1, 2022

Enrollment Period

10.1 years

First QC Date

February 27, 2012

Last Update Submit

April 19, 2022

Conditions

Keywords

hip fractureelderlydeliriumbroken hiphipsurgeryorthopedicorthopedic surgerypainanesthesiaOchsner ClinicOchsner HospitalLeslie Thomas MDNew OrleansLouisiana

Outcome Measures

Primary Outcomes (1)

  • number of participants developing delirium post-operatively

    3 days post-operatively

Secondary Outcomes (2)

  • the number of days admitted to the hospital post-operatively

    participants will be followed for the duration of the hospital stay, an expected average of 4 days

  • Is there a difference in pain scores between subjects receiving the femoral nerve catheter vs. opioid only therapy for hip fracture pain using the visual analog scale (VAS) and consumption of pain medication for breakthrough pain relief?

    post-op day 2 and again on post-op day 3

Study Arms (2)

Intravenous Opioids

ACTIVE COMPARATOR
Procedure: Intravenous Opioids

Femoral Nerve Catheterization

EXPERIMENTAL
Procedure: Femoral Nerve Catheterization

Interventions

A femoral nerve catheter will be placed prior to surgery in this group.

Also known as: FNC
Femoral Nerve Catheterization

Intravenous opioids will be given after surgery to provide pain relief to subjects assigned to this group.

Also known as: IV opioids
Intravenous Opioids

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 50 and older
  • Presenting to Ochsner Main Campus with a hip fracture

You may not qualify if:

  • Head trauma as reported in the medical record and/or patient response
  • High impact fractures as reported in the medical record
  • Aphasia as reported in the medical record and/or patient response
  • Deafness, blindness as reported in the medical record and/or patient response
  • True allergy (not sensitivity or side effects) to local anesthetics or opiates
  • Pregnant
  • Inability to complete study activities pre-operatively

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States

Location

MeSH Terms

Conditions

Hip FracturesDeliriumPain

Interventions

Analgesics, Opioid

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg InjuriesConfusionNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurocognitive DisordersMental Disorders

Intervention Hierarchy (Ancestors)

NarcoticsCentral Nervous System DepressantsPhysiological Effects of DrugsPharmacologic ActionsChemical Actions and UsesAnalgesicsSensory System AgentsPeripheral Nervous System AgentsCentral Nervous System AgentsTherapeutic Uses

Study Officials

  • Leslie Thomas, MD

    Ochsner Health System

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Anesthesiologist

Study Record Dates

First Submitted

February 27, 2012

First Posted

March 7, 2012

Study Start

March 1, 2012

Primary Completion

April 19, 2022

Study Completion

April 19, 2022

Last Updated

April 27, 2022

Record last verified: 2022-04

Locations