Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers

NCT01535898 | Completed

• 1 other identifier: 12-033
• Study Type: observational
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt. The purpose of this study is to determine if a new MR imaging method can help tumor evaluation in head and neck cancer or prostate cancer. The extra images will be obtained using Diffusion-weighted Magnetic Resonance Imaging which provides image contrast through detection of small restrictions in the movement of water molecules. This study may help us provide additional information about the tumor along with the picture of the organ.

Conditions

Head and Neck Cancer; Prostate Cancer

Keywords

MRI; MR imaging Pulse Sequence; High Resolution Diffusion-weighted; Questionnaire; 12-033

Outcome Measures

Primary Outcomes (1)

• feasibility of high resolution diffusion-weighted imaging

  using a new DWI pulse sequence from the manufacturer (General Electric Medical Systems (Milwaukee, WI)) for the assessment of head and neck cancer cancer and prostate cancer.

  2 years

Study Arms (1)

Pts having an MRI

This is a technology assessment protocol. The study is designed to assess the utility of the technology using a limited number of participants.

Other: MRI scanner with sequence

Interventions

MRI scanner with sequence OTHER

The intervention for the patients is the additional 10 minutes in the MRI scanner with sequence. The intervention for the volunteers is the scan, which will take a total of 30 minutes. The volunteers will have two more additional studies at 1-2 week intervals. Both the patients and volunteers will also need to fill out a questionnaire.

Pts having an MRI

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The radiologists on the study will identify potential research participants from those patients who are scheduled for MRI examination as part of their routine clinical care.

You may qualify if:

• Adults aged 18 and over.
• Men and women without regard to ethnic background.
• Patients/Subjects able to give informed consent
• Patients/Subjects whose weight does not exceed 275 lbs.
• Patient with a known or suspected head and neck cancer or prostate cancer scheduled for an MRI scan as part of their routine care --OR--
• Volunteer with no history of the disease in that category.

You may not qualify if:

• Patients who are unwilling or unable to undergo MRI including patients with contra-indications to MRI such as the presence of cardiac pacemakers or non-compatible intracranial vascular clips.

Sponsors & Collaborators

• Memorial Sloan Kettering Cancer Center: lead

Study Sites (1)

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States

Location

Related Links

• Memorial Sloan Kettering Cancer Center

MeSH Terms

Conditions

Head and Neck Neoplasms; Prostatic Neoplasms

Interventions

Base Sequence

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Genital Neoplasms, Male; Urogenital Neoplasms; Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Prostatic Diseases; Male Urogenital Diseases

Intervention Hierarchy (Ancestors)

Molecular Structure; Biochemical Phenomena; Chemical Phenomena; Genetic Structures; Genetic Phenomena

Study Officials

• Amita Dave, PhD

  Memorial Sloan Kettering Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 13, 2012
• First Posted: February 20, 2012
• Study Start: February 1, 2012
• Primary Completion: February 1, 2015
• Study Completion: February 1, 2015
• Last Updated: May 8, 2017

Record last verified: 2017-05

Locations

US (1)