Interpersonal Psychotherapy for Adolescent Girls

NCT01534377 | Completed DMC

• 2 other identifiers: 0354571R01MH091070-01A1
• Study Type: interventional
• Target: 328
• Locations: 1 country
• Sites: 1

Brief Summary

This study will evaluate the efficacy of Interpersonal Psychotherapy for Adolescents (IPT-A) for the treatment of depression and prevention of depression in maltreated and nonmaltreated girls between the ages of 13-15 years old.

Conditions

Depression

Keywords

Depression; Adolescents

Outcome Measures

Primary Outcomes (1)

• Change in adolescent depressive symptoms from baseline to post-intervention

  To evaluate the efficacy of Interpersonal Psychotherapy for Adolescents (IPT-A) for decreasing depressive symptoms and preventing depression in low-income ethnically and culturally diverse adolescent girls with and without histories of child maltreatment

  Baseline and 12 weeks, follow up at 1 year & again at 18 months post intervention

Study Arms (2)

Interpersonal Psychotherapy

EXPERIMENTAL

Adolescents will receive Interpersonal Psychotherapy for the treatment and prevention of depression.

Behavioral: Interpersonal Psychotherapy for Adolescents

Enhanced Care

EXPERIMENTAL

Adolescents will receive the Enhanced care model or care that they would typically receive in community setting to treat and prevent depression.

Behavioral: Enhanced Care

Interventions

Interpersonal Psychotherapy for Adolescents BEHAVIORAL

Adolescents will receive IPT-A a manualized intervention for depression and prevention of depression that emphasizes current interpersonal relationships, focusing on their immediate social context.

Also known as: IPT-A

Interpersonal Psychotherapy

Enhanced Care BEHAVIORAL

Adolescents will receive enhanced care which is consistent with care typically provided in community settings to treat and prevent depression.

Also known as: EC

Enhanced Care

Eligibility Criteria

• Age: 13 Years - 15 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• girls
• ages 13-15 years old
• low SES status
• live in Rochester or surrounding counties
• girls in the maltreated depressive symptom group will have CPS-documented child maltreatment
• girls in the nonmaltreated depressive symptom group will not have CPS- documented child maltreatment
• girls in the nonmaltreated nonsymptomatic comparison group will have no current or past mental illness and no documented child maltreatment

You may not qualify if:

• taking antidepressants or prescription medications for anxiety
• already receiving mental health treatment
• actively suicidal
• diagnosed with a severe mental disorder
• abusing drugs or alcohol
• evidence of compromised cognitive ability
• evidence of a pervasive developmental disorder
• evidence of a major physical or neurological disorder
• non-English speaking

Sponsors & Collaborators

• University of Rochester: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (1)

Mt. Hope Family Center

Rochester, New York, 14608, United States

Location

MeSH Terms

Conditions

Depression

Interventions

Interpersonal Psychotherapy

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Sheree Toth, PhD

  University of Rochester

  PRINCIPAL INVESTIGATOR

• Dante Cicchetti, Ph.D.

  University of Minnesota

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director Mt. Hope Family Center

Study Record Dates

• First Submitted: February 2, 2012
• First Posted: February 16, 2012
• Study Start: July 1, 2011
• Primary Completion: June 1, 2018
• Study Completion: June 1, 2018
• Last Updated: August 3, 2018

Record last verified: 2018-08

Locations

US (1)