NCT01531101

Brief Summary

The First Experimental Study on Transference work - In Teenagers (FEST-IT) will be a randomized clinical trial, which will be designed to explore effects of transference work in dynamic psychotherapy in adolescents with major depressive disorder (MDD). The design of the study is a so-called dismantling design, in which a single component is added and/or varied to an existent treatment method (psychodynamic psychotherapy). Thus, the efficiency of a specific technique (transference interventions) can be identified. The primary hypothesis is that the transference group may have a more favorable course over time than will the comparison group. The second hypothesis is that patients with a history of low Quality of Object Relations score and/or personality disorders-might benefit more from therapy with transference work than from therapy without. The third hypothesis is that female adolescents may have better treatment effect of transference work than male adolescents.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P25-P50 for not_applicable depression

Timeline
Completed

Started Jan 2012

Longer than P75 for not_applicable depression

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 8, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 10, 2012

Completed
7.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2019

Completed
Last Updated

March 17, 2020

Status Verified

March 1, 2020

Enrollment Period

7.2 years

First QC Date

February 8, 2012

Last Update Submit

March 16, 2020

Conditions

Depression

Keywords

Transference workPsychodynamicDepressionTreatmentAdolescent

Outcome Measures

Primary Outcomes (2)

  • Psychodynamic Functioning Scales (PFS)

    Average of 5 subscales rated by experienced clinician raters; family relations, friendships, tolerance for affects, insight, problem solving and adaptive capacity

    3 months

  • Inventory of Interpersonal Problems-Circumplex Version (IIP-C)

    64.items patient rated measure

    Currentl

Secondary Outcomes (4)

  • Global Assessment of Functioning (GAF)

    One week

  • Symptom Checklist-90 (Global Severity Index; GSI)

    Current

  • Beck Depression Inventory (BDI)

    Current

  • Montgomery Åsberg Rating Scale (MADRS)

    Current

Other Outcomes (1)

  • Adolescent Relationship Scale (ARS)

    Current

Study Arms (2)

Individual PDT with TW

EXPERIMENTAL

Individual Psychodynamic psychotherapy with transference work (TW).

Behavioral: Individual psychodynamic psychotherapy

Individual PDT without (TW)

ACTIVE COMPARATOR

Individual Psychodynamic psychotherapy without focus on transference work (TW).

Behavioral: Individual psychodynamic psychotherapy

Interventions

Individual psychodynamic psychotherapyBEHAVIORAL

Individual psychodynamic psychotherapy with or without transference work. I.e. with or without relational therapist interventions focusing on the patient-therapist relationship.

Also known as: Individual PDT, Short-term psychodynamic psychotherapy, Short-term dynamic psychotherapy, Short-term psychoanalytic psychotherapy
Individual PDT with TWIndividual PDT without (TW)

Eligibility Criteria

Age16 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Adolescents aged 16 - 18 years

You may not qualify if:

  • Pervasive developmental disorder,
  • psychosis, or substance abuse

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Research Unit, Division of

Tønsberg, Vestfold, 3103, Norway

Location

BUP vest, Diakonhjemmet sykehus

Oslo, Norway

Location

Nic Walls Institutt, Lovisenberg Diakonale Sykehus

Oslo, Norway

Location

Oslo University Hospital

Oslo, Norway

Location

Spcialist in psychiatry and clinical psychiatry

Oslo, Norway

Location

University of Oslo

Oslo, Norway

Location

Related Publications (7)

  • Calderon A, Storeide KAH, Elvejord C, Nissen-Lie HA, Ulberg R, Dahl HJ. Examining Psychotherapeutic Processes with Depressed Adolescents: A Comparative Study of Two Psychodynamic Therapies. Int J Environ Res Public Health. 2022 Dec 16;19(24):16939. doi: 10.3390/ijerph192416939.

    PMID: 36554820DERIVED

  • Brosholen P, Ulberg R, Dahl HJ, Thoren A. Therapists' Emotional Responses in Individual Therapy with Depressed Adolescents: An Evaluation of the Data Structure of the Feeling-Word Checklist-28. Int J Environ Res Public Health. 2022 Aug 2;19(15):9496. doi: 10.3390/ijerph19159496.

    PMID: 35954850DERIVED

  • Henriksen AK, Ulberg R, Tallberg BPU, Lovgren A, Johnsen Dahl HS. Conflicted Anger as a Central Dynamic in Depression in Adolescents-A Double Case Study. Int J Environ Res Public Health. 2021 Jun 15;18(12):6466. doi: 10.3390/ijerph18126466.

    PMID: 34203924DERIVED

  • Ulberg R, Hummelen B, Hersoug AG, Midgley N, Hoglend PA, Dahl HJ. The first experimental study of transference work-in teenagers (FEST-IT): a multicentre, observer- and patient-blind, randomised controlled component study. BMC Psychiatry. 2021 Feb 17;21(1):106. doi: 10.1186/s12888-021-03055-y.

    PMID: 33596856DERIVED

  • Lovgren A, Rossberg JI, Nilsen L, Engebretsen E, Ulberg R. How do adolescents with depression experience improvement in psychodynamic psychotherapy? A qualitative study. BMC Psychiatry. 2019 Mar 21;19(1):95. doi: 10.1186/s12888-019-2080-0.

    PMID: 30898111DERIVED

  • Ness E, Dahl HJ, Tallberg P, Amlo S, Hoglend P, Thoren A, Egeland J, Ulberg R. Assessment of dynamic change in psychotherapy with asdolescents. Child Adolesc Psychiatry Ment Health. 2018 Jul 30;12:39. doi: 10.1186/s13034-018-0246-z. eCollection 2018.

    PMID: 30069230DERIVED

  • Ulberg R, Hersoug AG, Hoglend P. Treatment of adolescents with depression: the effect of transference interventions in a randomized controlled study of dynamic psychotherapy. Trials. 2012 Sep 6;13:159. doi: 10.1186/1745-6215-13-159.

    PMID: 22950546DERIVED

Related Links

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Officials

  • Randi Ulberg, PhD

    Vestfold Hospital Trust and University of Oslo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Researcher

Study Record Dates

First Submitted

February 8, 2012

First Posted

February 10, 2012

Study Start

January 1, 2012

Primary Completion

March 1, 2019

Study Completion

March 1, 2019

Last Updated

March 17, 2020

Record last verified: 2020-03

Locations

NO(6)