Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness
Comparison of the Efficacy Between Pulsed Dye Laser (PDL) and the Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness: A Pilot, Prospective Randomized Trial.
1 other identifier
interventional
16
1 country
1
Brief Summary
The primary objective of this study is to compare the efficacy of PDL and the 1064-nm Nd:YAG laser in the treatment of facial redness.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2012
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2012
CompletedFirst Submitted
Initial submission to the registry
February 7, 2012
CompletedFirst Posted
Study publicly available on registry
February 9, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2012
CompletedDecember 2, 2021
November 1, 2021
7 months
February 7, 2012
November 30, 2021
Conditions
Outcome Measures
Primary Outcomes (2)
Rating on global improvement scale
Non-treating dermatologists will rate each side of the face using a global improvement scale to evaluate the effectiveness of the two treatments.
four months
Spectrophotometer measurement
Spectrophotometer measurement as the percent resolution on each follow up visit compared to baseline visit
four months
Secondary Outcomes (3)
Patient satisfaction
four months
Recorded discomfort
four months
Adverse events
four months
Study Arms (2)
YAG laser
EXPERIMENTALPulse Dye Laer
ACTIVE COMPARATORInterventions
This study involves treatments with two types of lasers, Pulsed dye lasers (PDL) and the 1064 nm Nd: YAG. Both lasers are FDA approved to treat vascularities in the skin.
Eligibility Criteria
You may qualify if:
- Healthy patients 18-55 years of age with erythematotelangiectatic rosacea (as verified by the the PI).
- Subjects who are willing to provide informed consent for participation in the study.
You may not qualify if:
- Pregnant or lactating individuals
- Subjects who are unable to understand the protocol or to give informed consent.
- Subjects who have a known history of photosensitive conditions (e.g. Systemic lupus, polymorphous light eruption)
- Subjects who have facial telangiectasia of diameter greater than 2 mm.
- Subject who have significant (as determined by the PI) acute inflammatory papules, pustules, and vesicle involving the central face.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Northwestern University Feinberg School of Medicine, Department of Dermatology
Chicago, Illinois, 60611, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Murad Alam, MD
Northwestern University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor in Dermatology, Otolaryngology - Head and Neck Surgery, and Surgery-Organ Transplantation
Study Record Dates
First Submitted
February 7, 2012
First Posted
February 9, 2012
Study Start
January 1, 2012
Primary Completion
August 1, 2012
Study Completion
August 1, 2012
Last Updated
December 2, 2021
Record last verified: 2021-11