Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence

NCT01528748 | Completed

• 1 other identifier: 15599
• Study Type: observational
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

This study examines the effectiveness of Cognitive Behavioral Analysis System of Psychotherapy (CBASP) in reducing both alcohol consumption and depressive symptoms in adults who are chronically depressed and alcohol dependent.

Conditions

Depressive Disorder; Major Depressive Disorder; Dysthymic Disorder; Alcohol-Related Disorders; Alcoholism

Outcome Measures

Primary Outcomes (2)

• Depression Rating

  Change in depression rating scale over time.

  Baseline and 20 weeks

• Drinking behavior

  Change in number of drinks consumed per day over time.

  Baseline and 20 weeks

Study Arms (1)

Chronically Depressed, Alcohol Dependent

Participants who have been formally diagnosed with a clinical diagnosis of Chronic Depression and Alcohol Dependence.

Behavioral: Cognitive Behavioral Analysis System of Psychotherapy

Interventions

Cognitive Behavioral Analysis System of Psychotherapy BEHAVIORAL

Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is a behavioral intervention that addresses the unique behavioral characteristics of chronically depressed individuals, most of which are highly relevant for alcoholics as well. CBASP has a structured, individualized, and collaborative (patient and clinician) design. The intervention emphasizes teaching effective coping strategies and employing motivational, cognitive, behavioral, and interpersonal techniques. Individual therapy (1 hour) sessions occur on a weekly basis for a total of 20 sessions over a period of 21 weeks.

Also known as: CBASP

Chronically Depressed, Alcohol Dependent

Eligibility Criteria

• Age: 21 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be recruited via a community sample.

You may qualify if:

• Clinical diagnosis of a current major depressive disorder (e.g., Major Depression, Dysthymic Disorder) for a minimum of two years
• Clinical diagnosis of alcohol dependence during the last thirty days
• Interest in changing one's drinking and alleviating depressive symptoms

You may not qualify if:

• Please call study site for additional information

Sponsors & Collaborators

• University of Virginia: lead

Study Sites (1)

University of Virginia Center for Addiction Research & Education (UVa CARE)

Charlottesville, Virginia, 22911, United States

Location

Related Publications (2)

• McCullough JP Jr. Treatment for chronic depression using Cognitive Behavioral Analysis System of Psychotherapy (CBASP). J Clin Psychol. 2003 Aug;59(8):833-46. doi: 10.1002/jclp.10176.

  PMID: 12858425 BACKGROUND

• McCullough, Jr., JP. (2001). Skills Training Manual for Diagnosis and Treating Chronic Depression: Cognitive Behavioral Analysis System of Psychotherapy (CBASP). New York: Guilford Press.

  BACKGROUND

MeSH Terms

Conditions

Depressive Disorder; Depressive Disorder, Major; Dysthymic Disorder; Alcohol-Related Disorders; Alcoholism

Condition Hierarchy (Ancestors)

Mood Disorders; Mental Disorders; Substance-Related Disorders; Chemically-Induced Disorders

Study Officials

• Jennifer K. Penberthy, Ph.D.

  University of Virginia, School of Medicine, Department of Psychiatry & Neurobehavioral Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, School of Medicine

Study Record Dates

• First Submitted: February 4, 2012
• First Posted: February 8, 2012
• Study Start: April 1, 2011
• Primary Completion: December 1, 2015
• Study Completion: July 1, 2018
• Last Updated: April 17, 2019

Record last verified: 2019-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)