NCT01505023

Brief Summary

The objective of this study was to test the efficacy of a partial meal replacement added with vitamins, minerals and inulin on weight reduction, blood lipids and micronutrients intake in obese Mexican women

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
179

participants targeted

Target at P50-P75 for phase_2 obesity

Timeline
Completed

Started Apr 2006

Shorter than P25 for phase_2 obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2006

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2006

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2007

Completed
4.9 years until next milestone

First Submitted

Initial submission to the registry

January 4, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 6, 2012

Completed
Last Updated

January 6, 2012

Status Verified

January 1, 2012

Enrollment Period

7 months

First QC Date

January 4, 2012

Last Update Submit

January 4, 2012

Conditions

Outcome Measures

Primary Outcomes (2)

  • Weight

  • Blood lipids

Secondary Outcomes (1)

  • Micronutrients intake

Study Arms (4)

Partial meal replacement

ACTIVE COMPARATOR
Dietary Supplement: Partial meal replacement

Partial meal replacement with inulin

EXPERIMENTAL
Dietary Supplement: Partial meal replacement with inulin

Inulin

ACTIVE COMPARATOR
Dietary Supplement: Inulin

No intervention

NO INTERVENTION

Interventions

Partial meal replacementDIETARY_SUPPLEMENT

The PMR was designed to contain sufficient amounts of all vitamins and minerals. Women were instructed to consume 2 servings per day at breakfast and dinner, each consisting of 33 g of powder dissolved in 250 ml of skim milk.

Partial meal replacement

The PMR was designed to contain sufficient amounts of all vitamins and minerals plus inulin. Women were instructed to consume 2 servings per day at breakfast and dinner, each consisting of 33 g of powder dissolved in 250 ml of skim milk.

Partial meal replacement with inulin
InulinDIETARY_SUPPLEMENT

Women were asked to consume one 5g serving of inulin mixed with any drink at breakfast and same amount at dinner (10 g of inulin/d).

Inulin

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Age GroupsAdult (18-64)

You may qualify if:

  • BMI \> 25 kg/m 2

You may not qualify if:

  • Pregnant
  • Lactating
  • Diagnosed with diabetes
  • Diagnosed with hypertension
  • Fasting glucose ≥126 mg/dL
  • Blood triglycerides ≥400mg/dL

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad Autónoma de Querétaro

Querétaro City, Querétaro, 76230, Mexico

Location

Related Publications (1)

  • Tovar AR, Caamano Mdel C, Garcia-Padilla S, Garcia OP, Duarte MA, Rosado JL. The inclusion of a partial meal replacement with or without inulin to a calorie restricted diet contributes to reach recommended intakes of micronutrients and decrease plasma triglycerides: a randomized clinical trial in obese Mexican women. Nutr J. 2012 Jun 18;11:44. doi: 10.1186/1475-2891-11-44.

MeSH Terms

Conditions

Obesity

Interventions

Inulin

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

StarchGlucansBiopolymersPolymersMacromolecular SubstancesDietary CarbohydratesCarbohydratesFructansPolysaccharides

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Research Coordinator

Study Record Dates

First Submitted

January 4, 2012

First Posted

January 6, 2012

Study Start

April 1, 2006

Primary Completion

November 1, 2006

Study Completion

February 1, 2007

Last Updated

January 6, 2012

Record last verified: 2012-01

Locations