Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis

NCT01504230 | Completed DMC

• 1 other identifier: 201104056RB
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury and even mortality. Identifying the factors related to falls occur within this population is essential for the development of effective regimes for fall prevention. The long-term objectives of this work are to ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs. The entire body's center of mass (CoM) is a critical indicator for balance control and the coordination among joints and muscles to control the CoM is still unclear. The aim1 of this study is to develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis. The aim2 of this study is to identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis. The findings of this research can provide needed information regarding the processes of balance control in this vulnerable osteoporosis population, and has the potential to be applied to individuals with other neuromuscular and orthopedic deficits.

Conditions

Osteoporosis

Keywords

To ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs.; To develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis.; To identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis.

Study Arms (2)

health older adults

Osteoporosis participants

Eligibility Criteria

• Age: 65 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

community sample

You may qualify if:

• for healthy older adults (OA)
• can stand for 5 minutes and walk for 6 minutes independently
• normal or corrected to normal vision
• an age between 65-85 years
• no osteoporosis (T-score above -2.5)
• for osteoporosis participants (OP)
• can stand for 5 minutes and walk for 6 minutes independently
• normal or corrected to normal vision
• an age between 65-85 years
• no osteoporosis (T-score below -2.5)

You may not qualify if:

• pregnant women
• cancer diagnosis
• sensory-motor deficits
• the BMI is larger than 30 or smaller than 18

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

School & Graduate Institute of Physical Therapy College of Medicine, National Taiwan University

Taipei, Taiwan

Location

MeSH Terms

Conditions

Osteoporosis

Condition Hierarchy (Ancestors)

Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Wei-Li Hsu, PhD

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 3, 2012
• First Posted: January 5, 2012
• Study Start: September 1, 2011
• Primary Completion: July 1, 2013
• Study Completion: July 1, 2013
• Last Updated: December 16, 2016

Record last verified: 2016-12

Locations

TW (1)