NCT01499901

Brief Summary

In France the indication of bilateral cochlear implant (CI) is limited to specific cases. The impact on perception and language of bilateral CI simultaneous versus sequential has to be established before discussing the enlargement of indications.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jan 2012

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 6, 2011

Completed
20 days until next milestone

First Posted

Study publicly available on registry

December 26, 2011

Completed
6 days until next milestone

Study Start

First participant enrolled

January 1, 2012

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2012

Completed
Last Updated

November 19, 2012

Status Verified

November 1, 2012

Enrollment Period

Same day

First QC Date

December 6, 2011

Last Update Submit

November 16, 2012

Conditions

Keywords

deafnessunilateral implantationbilateralauditory perception

Outcome Measures

Primary Outcomes (1)

  • Measurement of the score of perception of words in open list

    Measurement of the score of perception of words in open list in the noise 12 and 24 months after the implantation

    12 months after the implantation

Secondary Outcomes (5)

  • Measurement of the capability of localization right/left

    12 and 24 months after the implantation

  • Measurement of the level of comprehension and production

    24 months after the implantation

  • Evaluation of the medical monitoring about the materiovigilance and the eventual complications

    During all the duration of the study

  • Measurement of the vestibulometry and of the children's psychomotor development

    12 and 24 months after the implantation

  • Analysis of the parent questionnaires of the quality of life

    12 and 24 months after implantation

Study Arms (2)

sequential

EXPERIMENTAL

implantation bilateral sequential

Procedure: bilateral cochlear Implantation in sequential

simultaneous

EXPERIMENTAL

implantation bilateral simultaneous

Procedure: bilateral cochlear Implantation in simultaneous

Interventions

bilateral cochlear Implantation in sequential

sequential

bilateral cochlear Implantation in simultaneous

simultaneous

Eligibility Criteria

Age8 Months - 38 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Deep bilateral congenital deafness.
  • Age at the implantation: from 10 to 40 months, included.
  • Criteria for indication of unilateral implantation (those considered by the HAS (2007))
  • Deep bilateral deafness
  • Threshold prosthetic equal or above 60 dB
  • Intelligibility test in open list, below 30%, (to children under 3 years old : raw score in the questionnaire of the M.A.I.S. (72) below 15 with 2 apparatus)
  • No medical nor radiologic contraindication
  • Entitled child for welfare (excepted medical state aids)
  • French spoken at home
  • Agreement firms for the study by the two genitors

You may not qualify if:

  • Neurologic and/or psychiatric known related disorders
  • Malformation of the inner ear: the MRI scanners are routine examinations, in case of a cochlear implantation evaluation.
  • Progressive or acquired deafness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Deafness

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Nathalie Loundon, MD, MD-PhD

    Assistance Publique

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 6, 2011

First Posted

December 26, 2011

Study Start

January 1, 2012

Primary Completion

January 1, 2012

Study Completion

January 1, 2012

Last Updated

November 19, 2012

Record last verified: 2012-11