Contingency Management for Persons With Severe Mental Illness

NCT01478815 | Completed DMC

• 2 other identifiers: 12-070-3P30DA023918
• Study Type: interventional
• Target: 19
• Locations: 1 country
• Sites: 1

Brief Summary

Contingency management is efficacious for treating cocaine abuse, but contingency management interventions have rarely been applied to patients with severe and persistent mental health problems. This pilot project will estimate effect sizes of contingency management for reducing cocaine use in patients receiving psychiatric care at a large community based mental health program. In total, 30 cocaine abusing patients will be randomized to one of two 8-week treatment conditions: standard care or standard care with contingency management. Patients in both conditions will provide breath and urine samples for toxicology testing twice per week. In the contingency management condition, patients will receive the opportunity to win prizes for submitting cocaine negative urine samples. The investigators expect that patients receiving contingency management will evidence reductions in cocaine use and may show improvements in psychiatric symptoms and psychosocial functioning relative to patients in standard care. Effect size estimates obtained from this study will be used to guide larger scale and longer duration evaluations of contingency management for dually diagnosed patients.

Conditions

Substance Abuse

Outcome Measures

Primary Outcomes (1)

• longest continuous period of cocaine abstinence

  Week 8

Secondary Outcomes (1)

• other drug use and psychosocial problems

  Week 8

Study Arms (2)

Standard Care

PLACEBO COMPARATOR

Other: Standard Care

Contingency management for abstinence from drugs

EXPERIMENTAL

Behavioral: contingency management

Interventions

contingency management BEHAVIORAL

Participants will receive the opportunity to win prizes for submitting cocaine negative urine samples.

Contingency management for abstinence from drugs

Standard Care OTHER

Standard Care

Standard Care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age 18 years or older
• meet DSM-IV criteria for cocaine abuse or dependence
• English speaking
• pass a brief quiz regarding study procedures to ensure understanding of the informed consent process.

You may not qualify if:

• dementia
• in recovery from pathological gambling

Sponsors & Collaborators

• UConn Health: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Community Mental Health Affiliates, Inc.

New Britain, Connecticut, 06051, United States

Location

Related Publications (1)

• Petry NM, Alessi SM, Rash CJ. A randomized study of contingency management in cocaine-dependent patients with severe and persistent mental health disorders. Drug Alcohol Depend. 2013 Jun 1;130(1-3):234-7. doi: 10.1016/j.drugalcdep.2012.10.017. Epub 2012 Nov 20.

  PMID: 23182410 DERIVED

MeSH Terms

Conditions

Substance-Related Disorders

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Study Officials

• Nancy M Petry, Ph.D.

  UConn Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 21, 2011
• First Posted: November 23, 2011
• Study Start: December 1, 2011
• Primary Completion: August 1, 2012
• Study Completion: August 1, 2012
• Last Updated: April 9, 2019

Record last verified: 2019-04

Locations

US (1)