Exercise for Depression in Young People

NCT01474837 | Completed DMC

• 1 other identifier: H.E.A.L.T.H
• Study Type: interventional
• Target: 86
• Locations: 1 country
• Sites: 1

Brief Summary

Exercise as an adjunct to routine treatment may be useful for helping young people recover from distressing mental health problems, but they seldom get sufficient support to help them to exercise. The reasons for this may be that services cannot agree on the benefits of exercise, and the lack of reliable evidence showing the benefits of exercise in young people who use mental health services. Compliance with prescribed exercise is generally low, but the investigators think that relatively few young people will drop out of our specially designed programme. The investigators have found that young 'healthy' people may respond better if exercise is matched to their ability. The investigators are not sure if this would work with young people with mental health difficulties, so the investigators want to test it. The investigators have also found that our enabling exercise plan, with social support and motivational coaching, helps people with depression to take part, and not to drop out. The aims of our study are to see if exercise matched to their ability, with support in taking part, helps young people recover from distressing mental health difficulties. The investigators also want to ask young people how they feel about exercise as a part of their recovery. The investigators want to see if motivational coaching can help ongoing participation in exercise, and the investigators want to follow up the young people after six months to see if they are still doing exercise. The investigators believe that this study is important because it will help young people feel better about themselves, and improve their quality of life. This is an important national public health goal and should enable young people to grow into healthy adults, and maintain their health throughout adulthood. If our study is successful, the investigators believe that it has the potential to change the way in which mental health services deliver care to young people. If the investigators can help young people feel better about themselves, and improve their general health and well being through exercise, the investigators may reduce their reliance on mental health services. Research hypotheses A tailored exercise intervention will lead to significantly improved mental health outcomes and reduced exercise attrition rates in young people with depression.

Conditions

Depression

Keywords

depressive disorders; exercise therapy

Outcome Measures

Primary Outcomes (1)

• change in Children Depression Inventory score

  The CDI has 5 scales measuring negative mood, interpersonal difficulties, negative self-esteem, ineffectiveness and anhedonia. It is designed for 7-17 year olds, is sensitive to changes over the proposed timescale, quick to administer and yields an aggregate score indicating depressive illness and clinically significant depression.

  Baseline, Post-intervention (at 12 weeks), six months follow-up

Secondary Outcomes (3)

• change in Eq-5D score

  Baseline, post-intervention (6 weeks), six months follow-up

• Client Services Receipt Inventory

  Post intervention (6 weeks)

• Compliance with exercise

  post-intervention (6 weeks)

Study Arms (2)

Exercise with motivational interviewing

EXPERIMENTAL

Young people with depression exposed to exercise with motivational interviewing

Behavioral: Intervention: Exercise and motivational interviewing

Treatment as usual

NO INTERVENTION

Young people with depression receiving treatment as usual

Interventions

Intervention: Exercise and motivational interviewing BEHAVIORAL

12 sessions of exercise with MI

Also known as: Exercise arm

Exercise with motivational interviewing

Eligibility Criteria

• Age: 14 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Participants whose initial presenting problem is identified as depression will be eligible for the study

You may not qualify if:

• Young people, who at the time of the study, are unable to participate on account of any injury or physical health problem that precludes their participation, and those who are regular exercisers

Sponsors & Collaborators

• University of Nottingham: lead
• National Institute for Health Research, United Kingdom: collaborator

Study Sites (1)

University of Nottingham, School of Nursing, Midwifery & Physiotherapy

Nottingham, NG7 2HA, United Kingdom

Location

Related Publications (3)

• Turner D, Carter T, Sach T, Guo B, Callaghan P. Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK. BMJ Open. 2017 Nov 26;7(11):e016211. doi: 10.1136/bmjopen-2017-016211.

  PMID: 29180592 DERIVED

• Carter T, Guo B, Turner D, Morres I, Khalil E, Brighton E, Armstrong M, Callaghan P. Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial. BMC Psychiatry. 2015 Oct 14;15:247. doi: 10.1186/s12888-015-0638-z.

  PMID: 26467764 DERIVED

• Carter T, Callaghan P, Khalil E, Morres I. The effectiveness of a preferred intensity exercise programme on the mental health outcomes of young people with depression: a sequential mixed methods evaluation. BMC Public Health. 2012 Mar 13;12:187. doi: 10.1186/1471-2458-12-187.

  PMID: 22414319 DERIVED

MeSH Terms

Conditions

Depression; Depressive Disorder

Interventions

Motivational Interviewing; Exercise Test

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Mood Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Directive Counseling; Counseling; Mental Health Services; Behavioral Disciplines and Activities; Health Services; Health Care Facilities Workforce and Services; Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Ergometry; Investigative Techniques

Study Officials

• patrick Callaghan

  University of Nottingham

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 16, 2011
• First Posted: November 18, 2011
• Study Start: October 1, 2011
• Primary Completion: November 1, 2013
• Last Updated: January 17, 2014

Record last verified: 2014-01

Locations

GB (1)