Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique

NCT01474252 | Completed Phase 4 DMC

• 1 other identifier: SIRB213
• Study Type: interventional
• Target: 224
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate intubation duration between rapid sequence intubation technique (RSI) and non-rapid sequence intubation technique (non-RSI) performed by emergency medicine residents in Siriraj hospital.

Conditions

Tracheal Intubation Morbidity

Outcome Measures

Primary Outcomes (1)

• The overall intubation duration

  The overall intubation duration is recorded on the decision to intubation patient and corresponds to the time of confirmation the endotracheal position by chest auscultation

  Participants will be followed for the overall intubation duration until confirmation the endotracheal position, an expected average of 2 minutes

Secondary Outcomes (2)

• the intubation duration

  Participants will be followed for the intubation duration until confirmation the endotracheal position, an expected average of 5 minutes

• Complication

  Participants will be followed in the period of staying in the emergency room and hospital, an expected average of 4 weeks

Study Arms (2)

RSI technique

EXPERIMENTAL

Intubation with RSI technique. RSI technique includes the administration of inductive and neuromuscular blocking agents to facilitate an intubation. In this study, we have no restriction of medication use. Physicians can chose any of medication as an individual judgement.

Drug: RSI

Non-RSI

NO INTERVENTION

Intubation without RSI technique. No any medication use during intubation period.

Interventions

RSI DRUG

All medications are administered only one dose before intubation Anesthetics: Propofol 2-2.5 mg/kg Thiopental 3-5mg/kg Etomidate 1-2mg/kg Neuromuscular blocking agents: Succinylcholine 1-1.5mg/kg Rocuronium 0.9mg/kg Opioid: Fentanyl 1-2ug/kg

Also known as: Rapid Sequence Intubation

RSI technique

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patients required airway control by tracheal intubation

You may not qualify if:

• cardiac arrest

Sponsors & Collaborators

• Siriraj Hospital: lead

Study Sites (1)

Siriraj Hospital

Bangkok, Bangkok, 10700, Thailand

Location

MeSH Terms

Interventions

Rapid Sequence Induction and Intubation

Intervention Hierarchy (Ancestors)

Intubation, Intratracheal; Airway Management; Therapeutics; Intubation; Investigative Techniques

Study Officials

• Mingkwan Wongyingsinn, M.D.

  Siriraj Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: NON RANDOMIZED
• Masking: NONE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 9, 2011
• First Posted: November 18, 2011
• Study Start: July 1, 2008
• Primary Completion: December 1, 2012
• Study Completion: December 1, 2013
• Last Updated: June 2, 2016

Record last verified: 2016-06

Locations

TH (1)