NCT01458002

Brief Summary

This study targets two major risk factors for cancer; is designed to treat the behaviors on a population basis, using proactive recruitment strategies; intervenes on multiple behaviors simultaneously, thereby producing greater impacts for cancer prevention; utilizes one of the most promising approaches to low cost population based interventions for health-related behavior change, namely the internet; and develops and tests a promising new approach to increasing the utilization and effectiveness of internet-based interventions, relational agents. The primary aims are: (1) To develop and assess the effectiveness of a tailored internet intervention on a national sample; (2) To develop and assess the effectiveness of the internet intervention enhanced by a relational agent; and (3) To determine if the intervention with the relational agent can outperform the regular tailored internet intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,364

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2009

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

September 20, 2011

Completed
1 month until next milestone

First Posted

Study publicly available on registry

October 24, 2011

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
Last Updated

May 12, 2016

Status Verified

May 1, 2016

Enrollment Period

4.1 years

First QC Date

September 20, 2011

Last Update Submit

May 10, 2016

Conditions

Outcome Measures

Primary Outcomes (2)

  • Exercise

    Regular Exercise is defined as any planned physical activity (e.g., brisk walking, aerobics, jogging, bicycling, swimming, rowing, basketball, etc.) performed to increase physical fitness. Such activity should be performed 5 times or more per week for 30 minutes per session, consistent with CDC guidelines.

    Percentage of baseline at-risk participants who reach the Regular Exercise criteria at 24 months.

  • Sun Exposure

    Consistently protecting themselves from the sun every time they were out in the sun for 15+ minutes is defined as 1) using sunscreens with a sun protection factor (SPF) of 15 or more, wearing protective clothing (for example, a hat with a wide brim, shirts, and pants), and avoiding or limiting exposure to the sun during the mid-day hours (10 am - 4 pm).

    Percentage of baseline at-risk participants who reach the Sun Protection criteria at 24 months

Secondary Outcomes (2)

  • Exercise

    Increase in number of minutes of physical activity per week (150 minutes of moderate intensity or 75 minutes of vigorous intensity) measured by the International Physical Activity Questionnaire (IPAT)

  • Sun Exposure

    Increase in number of sun protection behaviors as measured by the Sun Protection Behavior Scale (SPBS), which consists of three scales: sunscreen use, sun avoidance and protective clothing, and hat use.

Study Arms (3)

Control

NO INTERVENTION

Assessment only

Tailored Internet Communications

OTHER

TTM expert system only

Other: Tailored Internet Communication with Relational AgentOther: Tailored Internet Communications

Tailored Internet Communication with Relational Agent

EXPERIMENTAL

TTM expert system plus relational agent

Other: Tailored Internet Communication with Relational Agent

Interventions

The Tailored Internet Intervention will include a "relational agent" component, which is an animated conversational agent that builds a working relationship with subjects over time and uses this alliance to boost intervention effectiveness and retention to the Tailored Internet Communications web site.

Tailored Internet Communication with Relational AgentTailored Internet Communications

Best practices for TTM tailored communications with two types of feedback: normative - compared to peers and ipsative - self compared to previous assessment.

Tailored Internet Communications

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • English speaking
  • access to computer
  • willing to download materials

You may not qualify if:

  • heart attack in past 6 months
  • kidney failure during dialysis
  • currently receiving chemotherapy or radiation for cancer
  • had a seizure in the past 6 months
  • had a leg or pelvic fracture in the past 6 months
  • legally blind
  • regularly use a wheelchair
  • (women only) currently pregnant or plan to be pregnant in the next 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Rhode Island

Kingston, Rhode Island, 02881, United States

Location

Related Publications (1)

  • Redding CA, Prochaska JO, Paiva A, Rossi JS, Velicer W, Blissmer BJ, Greene GW, Robbins ML, Sun X. Baseline stage, severity, and effort effects differentiate stable smokers from maintainers and relapsers. Subst Use Misuse. 2011;46(13):1664-74. doi: 10.3109/10826084.2011.565853. Epub 2011 Mar 30.

    PMID: 21449711BACKGROUND

MeSH Terms

Conditions

Sedentary BehaviorSkin Neoplasms

Condition Hierarchy (Ancestors)

BehaviorNeoplasms by SiteNeoplasmsSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Wayne F Velicer, PhD

    Univeristy of Rhode Island

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 20, 2011

First Posted

October 24, 2011

Study Start

April 1, 2009

Primary Completion

May 1, 2013

Study Completion

May 1, 2013

Last Updated

May 12, 2016

Record last verified: 2016-05

Data Sharing

IPD Sharing
Will not share

Locations