NCT01454492

Brief Summary

Allergic rhinitis is a complex chronic inflammatory disease, it always presents with nasal obstruction, nasal itching, sneezing and runny nose. Whether in adults or children, rhinitis is a complex disease. The prevalence of allergic rhinitis in Taiwan is about 24-29%. Taiwan is a developing country. It is a hot and humid country. In developing countries, industrialization, air pollution makes the constantly increasing number of patients with rhinitis. Penghu in 1994 for children aged 7 to 14 by the study found that among 7599 people, 1766 people have allergic rhinitis, about 23.2%. Allergic rhinitis is a complex chronic disease. So, it become a diagnostic challenge, its prevalence always underestimated. The prevalence of rhinitis has increased in recent years. The phenomenon of underestimate is caused by variety of personal and environmental factors. Allergic rhinitis had increased direct and indirect social and economic burden. Geographic tongue is a benign tongue performance. Geographic tongue has been reported their relevance to allergy. Geographic tongue is a chronic tongue situation. The causes of geographic tongue still remains unknown. Allergic rhinitis is a diagnostic challenge to clinicians. The investigators hope that geographic tongue could play a role in the diagnostic of allergic rhinitis. The prevalence of geographic tongue in the United States is about 1.8%, white Americans and Mexicans have a higher incidence rate. This study will investigate the relevance between allergic rhinitis and geographic tongue. The investigators will analyze the relevant gender, age, severity of inspection reports. The research results wound provide an important reference to the diagnosis of allergic rhinitis.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2011

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 4, 2011

Completed
15 days until next milestone

First Posted

Study publicly available on registry

October 19, 2011

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2012

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2012

Completed
Last Updated

October 19, 2011

Status Verified

October 1, 2011

Enrollment Period

6 months

First QC Date

October 4, 2011

Last Update Submit

October 18, 2011

Conditions

Keywords

Allergy rhinitisGeographic tongue

Outcome Measures

Primary Outcomes (1)

  • Number of participants with Adverse Events

    8th month

Study Arms (2)

Allergy rhinitis

Allergy rhinitis patients group

Non- Allergy rhinitis

Non- Allergy rhinitis patients group

Eligibility Criteria

Age20 Years - 89 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Group 1: Allergy rhinitis Group 2: Non-allergy rhinitis

You may qualify if:

  • rhinitis and non-rhinitis patients
  • willing to complete the study
  • no limitation of tongue movement

You may not qualify if:

  • more than 90 years old or younger than 20 years old
  • unable to complete the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

China Medical University Hospital

Taichung, Taiwan, 404, Taiwan

RECRUITING

Related Publications (5)

  • Miloglu O, Goregen M, Akgul HM, Acemoglu H. The prevalence and risk factors associated with benign migratory glossitis lesions in 7619 Turkish dental outpatients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Feb;107(2):e29-33. doi: 10.1016/j.tripleo.2008.10.015.

  • Reamy BV, Derby R, Bunt CW. Common tongue conditions in primary care. Am Fam Physician. 2010 Mar 1;81(5):627-34.

  • Masferrer E, Jucgla A. Images in clinical medicine. Geographic tongue. N Engl J Med. 2009 Nov 12;361(20):e44. doi: 10.1056/NEJMicm0810145. No abstract available.

  • Shulman JD, Carpenter WM. Prevalence and risk factors associated with geographic tongue among US adults. Oral Dis. 2006 Jul;12(4):381-6. doi: 10.1111/j.1601-0825.2005.01208.x.

  • Ugar-Cankal D, Denizci S, Hocaoglu T. Prevalence of tongue lesions among Turkish schoolchildren. Saudi Med J. 2005 Dec;26(12):1962-7.

MeSH Terms

Conditions

Rhinitis, AllergicGlossitis, Benign Migratory

Condition Hierarchy (Ancestors)

RhinitisNose DiseasesRespiratory Tract DiseasesRespiratory HypersensitivityOtorhinolaryngologic DiseasesHypersensitivity, ImmediateHypersensitivityImmune System DiseasesGlossitisTongue DiseasesMouth DiseasesStomatognathic Diseases

Study Officials

  • CJ Tai, M.D.

    China Medical University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2011

First Posted

October 19, 2011

Study Start

September 1, 2011

Primary Completion

March 1, 2012

Study Completion

September 1, 2012

Last Updated

October 19, 2011

Record last verified: 2011-10

Locations