NCT01448187

Brief Summary

The aim of the study is to describe the characteristics of patients treated with Iressa (particularly age, gender, phenotype, histology and stage of disease, line of treatment and previous treatments, smoking history, conditions of initiation of treatment (presence of an EGFR-activating mutation) and to evaluate the impact of treatment on the health of the population concerned in terms of morbidity and mortality (clinical benefit, safety,...) and quality of life

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
361

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2012

Typical duration for all trials

Geographic Reach
1 country

29 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 26, 2011

Completed
11 days until next milestone

First Posted

Study publicly available on registry

October 7, 2011

Completed
3 months until next milestone

Study Start

First participant enrolled

January 1, 2012

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
Last Updated

July 4, 2016

Status Verified

July 1, 2016

Enrollment Period

3.2 years

First QC Date

September 26, 2011

Last Update Submit

July 1, 2016

Conditions

Keywords

Lung cancer, France

Outcome Measures

Primary Outcomes (2)

  • The Overall survival

    24 months

  • The progression free survival

    24 months

Secondary Outcomes (6)

  • Description of Quality of life by Functional Assessment of Cancer Therapy - Lung including Life Stressor Checklist (FACT-L including LSC)

    baseline

  • Description of Quality of life by Functional Assessment of Cancer Therapy - Lung including Life Stressor Checklist (FACT-L including LSC)

    From baseline to 3 months

  • Description of Quality of life by Life Stressor Checklist - Lung (LSC-L)

    From 3 months to 6 months

  • Description of Quality of life by Life Stressor Checklist - Lung (LSC-L)

    From 6 months to 12 months

  • Description of Quality of life by Life Stressor Checklist - Lung (LSC-L)

    From 12 months to 18 months

  • +1 more secondary outcomes

Eligibility Criteria

AgeUp to 130 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Hospital, clinic

You may qualify if:

  • Patients treated with Iressa

You may not qualify if:

  • Patient included in a therapeutic trial comprising protocol use of Iressa
  • Patient included in a therapeutic trial (Huriet-Serusclat Act)
  • Patient refusing to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (29)

Research Site

Aulnay-sous-Bois, France

Location

Research Site

Bayonne, France

Location

Research Site

Bordeaux, France

Location

Research Site

Bron, France

Location

Research Site

Carcassonne, France

Location

Research Site

Chalon-sur-Saône, France

Location

Research Site

Cholet, France

Location

Research Site

Clamart, France

Location

Research Site

Colmar, France

Location

Research Site

Corbeil-Essonnes, France

Location

Research Site

Créteil, France

Location

Research Site

Épernay, France

Location

Research Site

La Source, France

Location

Research Site

Marseille, France

Location

Research Site

Mâcon, France

Location

Reseacrh Site

Metz, France

Location

Research Site

Mont-de-Marsan, France

Location

Research Site

Niort, France

Location

Research Site

Paris, France

Location

Research Site

Pierre-Bénite, France

Location

Research Site

Quimper, France

Location

Research Site

Reims, France

Location

Research Site

Rouen, France

Location

Research Site

Saint-Herblain, France

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Research Site

Saint-Nazaire, France

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Research Site

Saint-Omer, France

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Research Site

Strasbourg, France

Location

Research Site

Toulon, France

Location

Research Site

Vienne, France

Location

Related Links

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Thierry BOUILLET, Dr

    Bobigny

    PRINCIPAL INVESTIGATOR
  • Elisabeth BRAMBILLA, Pr

    Grenoble

    PRINCIPAL INVESTIGATOR
  • Jacques CADRANEL, Pr

    Paris

    PRINCIPAL INVESTIGATOR
  • Jean-Francois MORERE, Pr

    Bobigny

    PRINCIPAL INVESTIGATOR
  • Maurice PEROL, Dr

    Lyon

    PRINCIPAL INVESTIGATOR
  • Virginie RONDEAU, PhD

    Bordeaux

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 26, 2011

First Posted

October 7, 2011

Study Start

January 1, 2012

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

July 4, 2016

Record last verified: 2016-07

Locations