NCT01429428

Brief Summary

This is a randomized and controlled study to investigate if the far-IR radiation emitted by compression stockings fabric may be effective and safe as adjuvant treatment for cellulitis that affects the majority of women after puberty. The investigators expect that the far-IR effects on superficial microcirculation,deep dermis and subcutaneous fat may attenuate the clinical aspect of cellulitis.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2011

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2011

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 28, 2011

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 7, 2011

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2012

Completed
Last Updated

September 7, 2011

Status Verified

September 1, 2011

Enrollment Period

4 months

First QC Date

August 28, 2011

Last Update Submit

September 4, 2011

Conditions

Keywords

CellulitisSkin ultra-sound imagesTreatmentInfra-red light

Outcome Measures

Primary Outcomes (1)

  • Changes in ultra-sound images

    High resolution ultra-sound (DemaScan, Cortex Technology, Denmark)is used to measure dermis density and thickness and distance between dermis and fatty tissue in the most evident two areas with cellulitis(thighs and buttocks)

    0, 30, 60 and 90 days

Secondary Outcomes (9)

  • Changes in Cellulitis clinical grade

    0, 30, 60 and 90 days

  • Subject evaluation

    day 90th

  • Changes in Anthropometric measures

    0, 30, 60 and 90 days

  • Changes in Photographies

    0, 30, 60 and 90 days

  • Changes in Skin viscoelasticity

    0, 30, 60 and 90 days

  • +4 more secondary outcomes

Study Arms (2)

Stockings side one

PLACEBO COMPARATOR

This side of the compression stockings is just the fabric (placebo).

Other: No far-IR compression stockings

Stocking side two

ACTIVE COMPARATOR

This side of compression stocking emits far-IR radiation.

Other: Far-IR compression stockings

Interventions

The far-IR side of compression stocking will be used by subjects, during the day, for six hours a day, during 90 days.

Stocking side two

This side of compression stocking without far-IR radiation will be used by subjects, during the day, for six hours a day, during 90 days.

Stockings side one

Eligibility Criteria

Age25 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Signed Consent Form
  • Healthy women
  • Age: 25 to 40 years
  • Presence of cellulitis - II or III
  • No treatment for cellulitis in the last 6 months

You may not qualify if:

  • Pregnancy
  • Vascular disease
  • Psychiatric disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Cellulitis

Condition Hierarchy (Ancestors)

Skin Diseases, InfectiousInfectionsSuppurationConnective Tissue DiseasesSkin and Connective Tissue DiseasesInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Edileia Bagatin, M.D., PhD

    Universidade Federal de Sao Paulo, Brasil

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D., PhD - Professor

Study Record Dates

First Submitted

August 28, 2011

First Posted

September 7, 2011

Study Start

July 1, 2011

Primary Completion

November 1, 2011

Study Completion

March 1, 2012

Last Updated

September 7, 2011

Record last verified: 2011-09