Study of Prevalence of Colorectal Adenoma in 30- to 49-year-old Subjects With a Family History of Colorectal Cancer
Prevalence of Colorectal Adenoma in 30- to 49-year-old Asymptomatic Subjects With a First Relative History of Colorectal Cancer
1 other identifier
observational
1,000
1 country
1
Brief Summary
Current guidelines for initiating screening colonoscopies in patients younger than 50 years of age who have a first relative history of colorectal cancer are controversial. The aim of this study was to prospectively define the prevalence of colorectal adenoma 30- to 49-years-old asymptomatic subjects with a first relative history of colorectal cancer and to compare the data with controls. Design: Single-center prospective study
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2011
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2011
CompletedFirst Submitted
Initial submission to the registry
September 2, 2011
CompletedFirst Posted
Study publicly available on registry
September 5, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2014
CompletedSeptember 9, 2011
September 1, 2011
3 years
September 2, 2011
September 8, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
prevalence of colorectal adenoma(any size)
First screening colonoscopy
Secondary Outcomes (1)
prevalence of advanced adenoma
First screening colonoscopy
Study Arms (1)
Family history
30- to 49-year-old asymptomatic subjects with a first relative history of colorectal cancer
Eligibility Criteria
30- to 49-year-old asymptomatic subjects undergoing first screening colonoscopy because of a first relative history of colorectal cancer
You may qualify if:
- to 49-year-old asymptomatic subjects
- First relative history of colorectal cancer
You may not qualify if:
- previous colonoscopy for any reason
- personal history of colorectal adenomas or CRC
- history of familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, or inflammatory bowel disease
- documented history of occult GI bleeding, lower gastrointestinal tract bleeding not attributable to hemorrhoid, or
- iron deficiency anemia
- unexplained weight loss of \>10% of the body weight in the 6 months before colonoscopy
- incomplete examination of entire colon
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Asan Medical Center
Seoul, 138-736, South Korea
Biospecimen
whole blood and serum Colorectal polyp/cancer tissue
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Kyung-Jo Kim, M.D
Department of Gastroenterology, Asan Medical Center
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Assistant Professor
Study Record Dates
First Submitted
September 2, 2011
First Posted
September 5, 2011
Study Start
September 1, 2011
Primary Completion
September 1, 2014
Study Completion
September 1, 2014
Last Updated
September 9, 2011
Record last verified: 2011-09