NCT01416272

Brief Summary

The objective of this twelve month dispensing study is to evaluate the clinical performance, particularly comfort and vision, of KeraSoft IC Soft Contact Lenses.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2011

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2011

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 11, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 15, 2011

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2013

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

November 25, 2014

Completed
Last Updated

November 25, 2014

Status Verified

November 1, 2014

Enrollment Period

1.7 years

First QC Date

August 11, 2011

Results QC Date

November 18, 2014

Last Update Submit

November 18, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • Comfort

    Symptoms and complaints measured on an analog scale

    4 visits over 1 year

Secondary Outcomes (2)

  • Visual Acuity - Low Contrast

    4 visits over 1 year

  • Visual Acuity - High Contrast

    4 visits over 1 year

Study Arms (1)

KeraSoft IC Soft Contact Lenses

EXPERIMENTAL

KeraSoft IC Soft Contact Lenses, with CIBA Clear Care solution provided for lens care

Device: KeraSoft IC Soft Contact Lenses

Interventions

Lenses will be worn between 8 and 16 hrs each day, for 12 months

KeraSoft IC Soft Contact Lenses

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have participated and completed a previous study (ROC2-10-078).
  • Is Keratoconic

You may not qualify if:

  • Has any systemic disease affecting ocular health.
  • Is using any systemic or topical medications that will, in the Investigator's opinion, affect ocular physiology or lens performance.
  • Is not correctable to 20/50 or better in each eye with contact lenses.
  • Has greater than Grade 2 slit lamp exam findings.
  • Has any atypical scar for a keratoconic or neovascularization within the central 4mm of the cornea. Subjects with minor peripheral corneal scarring that, in the Investigator's judgment, does not interfere with contact lens wear are eligible for this study.
  • Has any neovascularization within the central 4mm of the cornea.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch & Lomb Incorporated

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Keratoconus

Condition Hierarchy (Ancestors)

Corneal DiseasesEye Diseases

Results Point of Contact

Title
Robert Steffen, OD, MS
Organization
Bausch & Lomb / Valeant Pharmaceuticals

Study Officials

  • Robert Steffen, OD, MS

    Bausch & Lomb Incorporated

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 11, 2011

First Posted

August 15, 2011

Study Start

April 1, 2011

Primary Completion

December 1, 2012

Study Completion

February 1, 2013

Last Updated

November 25, 2014

Results First Posted

November 25, 2014

Record last verified: 2014-11

Locations