Inspiratory Muscle Training in Pulmonary Hypertension
Inspiratory Muscle Training Effect on the Functional Capacity and the Quality of Life in Chronic Pulmonary Hypertension
1 other identifier
interventional
34
1 country
1
Brief Summary
The purpose of this study is evaluate the effect the inspiratory muscle training on the functional capacity of patients with pulmonary hypertension.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Dec 2009
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2009
CompletedFirst Submitted
Initial submission to the registry
April 20, 2011
CompletedFirst Posted
Study publicly available on registry
August 5, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2011
CompletedAugust 5, 2011
August 1, 2011
1.8 years
April 20, 2011
August 4, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The distance traveled in meters in the six minutes walk test after 8 weeks the inspiratory muscle training
patients will be monitored throughout the training protocol for 8 weeks
Secondary Outcomes (1)
Increase in score of quality of life questionnaire after 8 weeks the inspiratory muscle training
patients will be monitored throughout the training protocol for 8 weeks
Interventions
The load is adjusted weekly in thirty percent of maximal inspiratory pressure of the subject.
Eligibility Criteria
You may qualify if:
- Clinical diagnosis pulmonary hypertension
- World Health Organization (WHO) functional class II to IV
- inspiratory muscle weakness
You may not qualify if:
- obesity
- chronic obstructive pulmonary disease
- orthopedic and neurological disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hospital de Clinica de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035003, Brazil
Related Publications (2)
Dall'Ago P, Chiappa GR, Guths H, Stein R, Ribeiro JP. Inspiratory muscle training in patients with heart failure and inspiratory muscle weakness: a randomized trial. J Am Coll Cardiol. 2006 Feb 21;47(4):757-63. doi: 10.1016/j.jacc.2005.09.052. Epub 2006 Jan 26.
PMID: 16487841RESULTMereles D, Ehlken N, Kreuscher S, Ghofrani S, Hoeper MM, Halank M, Meyer FJ, Karger G, Buss J, Juenger J, Holzapfel N, Opitz C, Winkler J, Herth FF, Wilkens H, Katus HA, Olschewski H, Grunig E. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation. 2006 Oct 3;114(14):1482-9. doi: 10.1161/CIRCULATIONAHA.106.618397. Epub 2006 Sep 18.
PMID: 16982941RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Pedro Dal'Lago
Hospital de Clínicas de Porto Alegre
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
April 20, 2011
First Posted
August 5, 2011
Study Start
December 1, 2009
Primary Completion
September 1, 2011
Study Completion
December 1, 2011
Last Updated
August 5, 2011
Record last verified: 2011-08