Functional MRI and MRA in Migraine With Aura
1 other identifier
observational
80
1 country
1
Brief Summary
Patients who report that exposure to bright light or strenuous physical activity will induce migraine aura will be provoked using one or both of these methods. Followingly the patients will be examined by functional MRI. Íf the patients develop migraine headache, MR angiography will be performed as well. The primary study hypothesis is that the functional MRI signal will show features similar to those of the electrophysiological phenomenon of cortical spreading depression.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2010
CompletedFirst Submitted
Initial submission to the registry
July 5, 2011
CompletedFirst Posted
Study publicly available on registry
July 7, 2011
CompletedJuly 7, 2011
May 1, 2011
July 5, 2011
July 5, 2011
Conditions
Eligibility Criteria
Patients diagnosed with migraine with aura
You may qualify if:
- Diagnosed with migraine with aura as defined by The International Classification of Headache Disorders 2
- Age between 18 and 80 years both inclusive
- Reports that bright light or strenuous physical activity may trigger migraine aura
You may not qualify if:
- Contraindications towards exposure to photostimulation or strenuous exercise
- Body weight above 130 kg
- Pregnant or lactating females
- Contraindications towards MRI scanning
- History or clinical signs of: cardiovascular disease, psychiatric disease, substance abuse or any symptom or disease considered relevant by the examining physician.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Danish Headache Center
Glostrup Municipality, 2600, Denmark
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
July 5, 2011
First Posted
July 7, 2011
Study Start
December 1, 2010
Last Updated
July 7, 2011
Record last verified: 2011-05