NCT01387451

Brief Summary

Retrospective studies have combined positron-emission tomography and computed tomography (PET-CT) to identify adipose tissue with a high rate of uptake of 18F-fluorodeoxyglucose(18F-FDG) as active brown adipose tissue(BAT). In addition, biopsy specimens and immunohistochemical staining with a UCP1-specific antiserum were used to indicate that normal adults were able to have BAT. However,these studies only chose few subjects and limited to the neck tissue. Therefore, the investigators intend to test BAT in different parts of adults and analyse the clinical factors.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2010

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2010

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

June 30, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 4, 2011

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
Last Updated

July 4, 2011

Status Verified

April 1, 2010

Enrollment Period

3.2 years

First QC Date

June 30, 2011

Last Update Submit

July 1, 2011

Conditions

Obesity

Keywords

Brown adipose tissueDifferent regionsChinese adults

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects who underwent surgical therapy from 2010 to 2013 in Huashan Hospital and the operation scope includes brown adipose tissue sample sites.

You may qualify if:

  • Subjects who underwent surgical therapy and the operation scope includes BAT sample sites.

You may not qualify if:

  • Pregnant women
  • With implantable medical electronic instrument
  • Younger than 18 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Huashan Hospital

Shanghai, Shanghai Municipality, 200040, China

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Adipose tissue, plasma

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Yiming Li, Doctor

    Huashan Hospital

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 30, 2011

First Posted

July 4, 2011

Study Start

October 1, 2010

Primary Completion

December 1, 2013

Study Completion

December 1, 2013

Last Updated

July 4, 2011

Record last verified: 2010-04

Locations

CN(1)