NCT01385969

Brief Summary

The purpose of this study is to determine if using 20 mL B.Braun syringes to inflate LMAs and allowing them to recoil will put the pressure of the LMA cuff within the safety range. It will also determine if remaining within this safety range has an effect on complications after surgery..

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
360

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2011

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
27 days until next milestone

First Submitted

Initial submission to the registry

June 28, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 30, 2011

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2013

Completed
Last Updated

November 6, 2015

Status Verified

November 1, 2015

Enrollment Period

1.8 years

First QC Date

June 28, 2011

Last Update Submit

November 5, 2015

Conditions

Keywords

overinflation of LMAs

Outcome Measures

Primary Outcomes (1)

  • Pressure of the syringe after inflation of the LMA cuff

    after inflation, 1 hour into surgery

Secondary Outcomes (1)

  • Number of patients with dysphagia and/or dysphonia

    1, 2, and 24 hours after surgery

Study Arms (3)

Standard Practice

Device: Standard inflation of LMA cuff

Syringe recoil

Device: Pressure check with syringe recoil

Pressure Transducer

Device: Pressure check by pressure transducer

Interventions

LMA cuff will be inflated per standard practice with a syringe and resulting cuff pressure will be measured by manual palpation of the cuff per standard practice.

Also known as: LMA inflation routine clinical practice
Standard Practice

LMA cuff will be inflated per standard practice with a syringe and resulting cuff pressure will be measured by syringe recoil

Also known as: LMA cuff pressure by syringe recoil
Syringe recoil

LMA cuff will be inflated per standard practice with a syringe and resulting cuff pressure will be measured by pressure transducer.

Also known as: LMA cuff pressure checked by pressure transducer
Pressure Transducer

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients scheduled to undergo a surgical procedure less than 2 hours in duration

You may qualify if:

  • Registered Mayo Clinic in Florida patients scheduled to undergo a surgery
  • Planned use of LMA during surgery
  • between the ages of 18-99
  • short duration (\<2 hours elective surgery)

You may not qualify if:

  • recent history of upper respiratory tract infection
  • intra-cavitary or laparoscopic procedure
  • risk of pulmonary aspiration
  • known difficult airway
  • history of gastric reflux
  • BMI \> 40
  • lateral or prone positions
  • oral or nasal surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Florida College of Medicine

Gainesville, Florida, 32610, United States

Location

Mayo Clinic

Jacksonville, Florida, 32224, United States

Location

MeSH Terms

Conditions

PharyngitisDeglutition DisordersDysphonia

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsPharyngeal DiseasesStomatognathic DiseasesRespiratory Tract DiseasesOtorhinolaryngologic DiseasesEsophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesVoice DisordersLaryngeal DiseasesNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Christopher Robards, MD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

June 28, 2011

First Posted

June 30, 2011

Study Start

June 1, 2011

Primary Completion

April 1, 2013

Study Completion

April 1, 2013

Last Updated

November 6, 2015

Record last verified: 2015-11

Locations