NCT01384487

Brief Summary

The primary objective of this clinical study is to compare the Nidek RS-3000 Optical Coherence Tomography (OCT) device to the Optovue RTVue OCT. The secondary objective is to evaluate any adverse events found during the clinical study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
89

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

June 27, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 29, 2011

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2011

Completed
Last Updated

February 20, 2012

Status Verified

February 1, 2012

Enrollment Period

5 months

First QC Date

June 27, 2011

Last Update Submit

February 17, 2012

Conditions

Keywords

Viewing and axial cross sectional imaging of ocularstructures, including the anterior chamber

Outcome Measures

Primary Outcomes (9)

  • Total Retinal Thickness

    One Visit

  • Inner Retinal Thickness

    One Visit

  • Outer Retinal Thickness

    One Visit

  • RNFL Thickness

    One Visit

  • Optic Disc Analysis

    One Visit

  • G Chart

    One Visit

  • Anterior Chamber Angle Image

    One Visit

  • SLO Image

    One Visit

  • Pachymetry

    One Visit

Secondary Outcomes (1)

  • Any adverse events

    One Visit

Study Arms (4)

Normal Eyes

Eyes without disease

Eyes with Glaucoma

Eyes with Retinal Disease

Eyes with Corneal Disease

Including post keratorefractive surgery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Primary care clinic

You may qualify if:

  • Subjects of legal age and who have full legal capacity to volunteer on the date the informed consent is signed.
  • Subjects who follow the instructions by Principal/Clinical Investigator or clinical staff at the clinical site, and can visit on a scheduled examination date.
  • Subjects who sign an informed consent form to participate in the clinical study.
  • Subjects who agree to take the qualifying examination and RS-3000 and RTVue data acquisition.

You may not qualify if:

  • Diabetes mellitus (DM) and/or diabetic retinopathy
  • Hypertension (HT)
  • Cerebral infarction, cerebral hemorrhage, cranial nerve neoplasm and other central nervous system diseases affecting vision
  • Cardiac, hepatic, renal and hematologic diseases
  • Current systemic administration of steroid
  • History of anticancer agent etc.
  • Optically-stimulated epileptic seizure
  • Dementia
  • Subjects who have other life threatening and debilitating systemic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hamilton Glaucoma Center

La Jolla, California, 92093-0946, United States

Location

MeSH Terms

Conditions

GlaucomaRetinal DiseasesCorneal Diseases

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases

Study Officials

  • Robert Weinreb, M.D.

    UCSD, Hamilton Glaucoma Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 27, 2011

First Posted

June 29, 2011

Study Start

June 1, 2011

Primary Completion

November 1, 2011

Study Completion

November 1, 2011

Last Updated

February 20, 2012

Record last verified: 2012-02

Locations