Key Insights

Highlights

Success Rate

78% trial completion

Published Results

17 trials with published results (15%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.0%

14 terminated out of 117 trials

Success Rate

77.8%

-8.7% vs benchmark

Late-Stage Pipeline

9%

10 trials in Phase 3/4

Results Transparency

35%

17 of 49 completed with results

Key Signals

17 with results78% success14 terminated

Data Visualizations

Phase Distribution

70Total
Not Applicable (32)
Early P 1 (1)
P 1 (15)
P 2 (12)
P 3 (6)
P 4 (4)

Trial Status

Completed49
Recruiting24
Unknown18
Terminated14
Active Not Recruiting4
Enrolling By Invitation3

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 49 completed trials

Clinical Trials (117)

Showing 20 of 20 trials
NCT07530783Not ApplicableTerminatedPrimary

Defining Retinal and Choroidal Structures Using Hyperspectral Imaging

NCT06451068Not ApplicableWithdrawnPrimary

Peripheral Retina Robotically Aligned OCT Study

NCT06455826Phase 1Completed

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

NCT01432847RecruitingPrimary

Cell Collection to Study Eye Diseases

NCT01145196Recruiting

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene

NCT01496625Recruiting

National Eye Institute Biorepository for Retinal Diseases

NCT06627179Phase 2Recruiting

Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

NCT06841575Not ApplicableRecruiting

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

NCT06891443Phase 3Recruiting

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

NCT07458516Recruiting

Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients

NCT07401459Not ApplicableNot Yet Recruiting

A Multimodal AI Agent for Ophthalmic Clinical Decision Support

NCT07149740RecruitingPrimary

Data Gathering for A10900

NCT03846193Phase 1Terminated

FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD

NCT06380075Not ApplicableRecruitingPrimary

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

NCT06455384Not ApplicableRecruiting

The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

NCT07006649Not ApplicableRecruiting

CHOPXE - Analysis of Choriocapillaris Flow Deficits in Patients With Pseudoxanthoma Elasticum

NCT04636307Completed

Characterization of Retinal Disease Progression in Eyes With Non Proliferative Diabetic Retinopathy in Diabetes Type 2 Using Non-invasive Procedures (CHART)

NCT06852963Phase 1Recruiting

A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001

NCT03713268Recruiting

Intraoperative OCT Guidance of Intraocular Surgery II

NCT06139523RecruitingPrimary

Optimize Pediatric OCT Imaging

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