Key Insights

Highlights

Success Rate

79% trial completion

Published Results

17 trials with published results (14%)

Research Maturity

52 completed trials (43% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.7%

14 terminated out of 120 trials

Success Rate

78.8%

-7.8% vs benchmark

Late-Stage Pipeline

8%

10 trials in Phase 3/4

Results Transparency

33%

17 of 52 completed with results

Key Signals

17 with results79% success14 terminated

Data Visualizations

Phase Distribution

70Total
Not Applicable (32)
Early P 1 (1)
P 1 (15)
P 2 (12)
P 3 (6)
P 4 (4)

Trial Status

Completed52
Recruiting22
Unknown18
Terminated14
Active Not Recruiting6
Withdrawn3

Trial Success Rate

78.8%

Benchmark: 86.5%

Based on 52 completed trials

Clinical Trials (120)

Showing 20 of 20 trials
NCT01145196Recruiting

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene

NCT06627179Phase 2Active Not Recruiting

Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

NCT01496625Recruiting

National Eye Institute Biorepository for Retinal Diseases

NCT03076697Completed

Smartphone Screening for Eye Diseases

NCT03011541Not ApplicableRecruitingPrimary

Stem Cell Ophthalmology Treatment Study II

NCT06891443Phase 3Recruiting

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

NCT06455384Not ApplicableRecruiting

The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

NCT06269666Not ApplicableCompletedPrimary

P200TxE Diseased Eye Image Collection

NCT01432847RecruitingPrimary

Cell Collection to Study Eye Diseases

NCT07651943CompletedPrimary

AI-Assisted Interpretation of Ultra-Widefield Retinal Images

NCT07641738Not Yet Recruiting

Collecting Data on Retinal Blood Blood Flow and Blood Vessel Shape/Appearance Using an Investigational Device, XyCAM CRE, and to Then Compare Those Images With Images Collected From a Patient's Routine Clinical Examination.

NCT07628946Recruiting

Establishment of a Multimodal Standard Database for Inflammation-related Ophthalmopathy

NCT06455826Phase 1Completed

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

NCT06852963Phase 1Active Not Recruiting

A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001

NCT02435940Recruiting

Inherited Retinal Degenerative Disease Registry

NCT06380075Not ApplicableRecruitingPrimary

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

NCT07530783Not ApplicableTerminatedPrimary

Defining Retinal and Choroidal Structures Using Hyperspectral Imaging

NCT06451068Not ApplicableWithdrawnPrimary

Peripheral Retina Robotically Aligned OCT Study

NCT06841575Not ApplicableRecruiting

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

NCT07458516Recruiting

Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients

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Research Network

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