NCT01377350

Brief Summary

The purpose of this study is to explore the feasibility of monitoring hemodynamic changes, which result from heart failure exacerbations, by recording the respiratory effort, chest wall dynamics and quantifying the development of dyspnea by using miniature mechanical sensors that are attaches to the chest.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable heart-failure

Timeline
Completed

Started Jun 2011

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 18, 2011

Completed
14 days until next milestone

Study Start

First participant enrolled

June 1, 2011

Completed
20 days until next milestone

First Posted

Study publicly available on registry

June 21, 2011

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

June 21, 2011

Status Verified

March 1, 2011

Enrollment Period

1.5 years

First QC Date

May 18, 2011

Last Update Submit

June 20, 2011

Conditions

Keywords

Heart failuremonitoring

Outcome Measures

Primary Outcomes (1)

  • earliest non-invasive signs for lung congestion and deterioration in the heart failure

    Exploring the feasibility of monitoring hemodynamic changes, which result from heart failure exacerbations, by recording the respiratory effort, chest wall dynamics and quantifying the development of dyspnea by using miniature mechanical sensors that are attaches to the chest.

    18 months

Study Arms (1)

"Pneumedicare"s monitoring system

EXPERIMENTAL

Single arm study - "Pneumedicare"s monitoring system is used for monitoring heart failure patients

Device: "Pneumedicare"s monitoring system.Device: "Pneumedicare"s monitoring system

Interventions

Non invasive clinical follow-up of patients with HF deterioration and improvement, by a device-based algorithm. The system comprises of patches attached to the patients' thorax that include motion sensors (Accelerometers) that measure the chest wall dynamics and the mechanics of lung inflation and deflation.

Also known as: "Pneumedicare"s monitoring system for heart failure patients
"Pneumedicare"s monitoring system

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Acute decompensated HF
  • Decompensated chronic HF in patients with NYHA class III-IV symptoms
  • Age over 20 years
  • Ejection fraction reduced below 35% OR doppler evidence of impaired left ventricular diastolic filling

You may not qualify if:

  • Inability or unwillingness to follow the study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rambam Health Care Campus

Haifa, 31096, Israel

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Shmuel Rispler, MD PhD

    Rambam Medical Center Haifa Israel

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Shmuel rispler, MD PhD

CONTACT

Amir Landesberg, MD PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 18, 2011

First Posted

June 21, 2011

Study Start

June 1, 2011

Primary Completion

December 1, 2012

Study Completion

December 1, 2012

Last Updated

June 21, 2011

Record last verified: 2011-03

Locations