NCT01369238

Brief Summary

  1. 1.Purpose of study
  2. 2.To evaluate the efficacy of East-West collaborative medicine using Bee-Venom Acupuncture Therapy on Whiplash-Associated Disorders using VAS scale
  3. 3.To evaluate the efficacy of East-West collaborative medicine using Bee-Venom Acupuncture Therapy on Whiplash-Associated Disorders using NDI, BDI, SF-36, and EQ-5D.
  4. 4.Interventions \& Groups
  5. 5.group 1: Bee-Venom Acupuncture Therapy
  6. 6.group 2: zaltoprofen
  7. 7.group 3: Bee-Venom Acupuncture Therapy \& zaltoprofen

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2011

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 12, 2011

Completed
20 days until next milestone

Study Start

First participant enrolled

June 1, 2011

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 8, 2011

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2012

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2012

Completed
Last Updated

June 8, 2011

Status Verified

June 1, 2011

Enrollment Period

7 months

First QC Date

May 12, 2011

Last Update Submit

June 7, 2011

Conditions

Keywords

bee venom acupunctureeast west collaborative medicinewhiplash associated disorder

Outcome Measures

Primary Outcomes (1)

  • pain scores on Visual Analogue Scale

    changes from baseline in VAS at 1 month

Secondary Outcomes (4)

  • neck disability scores on Neck Disability Index

    changes from baseline in NDI at 1 month

  • depression scores on Beck Depression Inventory

    changes from baseline in BDI at 1 month

  • quality of life scores on short form SF-36

    changes from baseline in short form SF-36 at 1 month

  • quality of life scores on EQ-5D

    changes from baseline in EQ-5D at 1 month

Study Arms (3)

Bee Venom Acupuncture & zaltoprofen

EXPERIMENTAL
Device: Bee Venom Acupuncture TherapyDrug: zaltoprofen

zaltoprofen

ACTIVE COMPARATOR
Drug: zaltoprofen

Bee Venom Acupuncture

ACTIVE COMPARATOR
Device: Bee Venom Acupuncture Therapy

Interventions

1:4000, SC 1cc/day, 2\~3days/wk, for 1 month

Also known as: pharmacoacupuncture
Bee Venom AcupunctureBee Venom Acupuncture & zaltoprofen

80mg/Tab, per os 1Tab tid, for 2 months

Also known as: soleton
Bee Venom Acupuncture & zaltoprofenzaltoprofen

Eligibility Criteria

Age25 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • clinical diagnosis of Whiplash injuries
  • Must have cervicalgia of more than VAS 5

You may not qualify if:

  • cancer, osteoporosis, ankylosing spodylitis, cauda equina syndrome, infection
  • spinal operation
  • other musculoskeletal pain
  • physicological or mental disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Whiplash Injuries

Interventions

Acupuncture Therapypyranoprofen

Condition Hierarchy (Ancestors)

Neck InjuriesWounds and Injuries

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeutics

Study Officials

  • Seok-Hee Chung

    Kyung Hee Oriental Medical Center

    STUDY CHAIR
  • Jun-Hwan Lee

    Kyung Hee University Hospital at Gangdong

    STUDY DIRECTOR
  • Koh-Woon Kim

    Kyung Hee Oriental Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 12, 2011

First Posted

June 8, 2011

Study Start

June 1, 2011

Primary Completion

January 1, 2012

Study Completion

March 1, 2012

Last Updated

June 8, 2011

Record last verified: 2011-06