NCT01364753

Brief Summary

Our overall goal has been twofold: 1) to evaluate whether there are significant age-related changes in flight simulator performance near age 60, and 2) to assess whether there is an alternative model that can explain longitudinal flight simulator performance on the basis of measures of cognitive function and expertise.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
139

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2006

Completed
5.4 years until next milestone

First Submitted

Initial submission to the registry

May 31, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 2, 2011

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2014

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

December 6, 2016

Status Verified

December 1, 2016

Enrollment Period

8.4 years

First QC Date

May 31, 2011

Last Update Submit

December 5, 2016

Conditions

Memory Impairment

Keywords

MemoryAviation

Outcome Measures

Primary Outcomes (1)

  • Aviation-related performance over time.

    Participants "fly" in our computerized flight simulator and perform a set of brief tasks designed to measure reaction time and attention span. The study is longitudinal, collecting information about aviation-related performance over time. There is an initial training period, followed by annual visits. During the training period participants learn how to "fly" the simulator, and performance on certain standard maneuvers will be measured during a maximum of 6 simulated flights. At each annual visit, participants fly two 75-minute simulated flights and may be asked to perform up to four holding patterns and instrument landings.

    longitudinal

Study Arms (1)

Pilots

No intervention; observational study

Eligibility Criteria

Age45 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

healthy older pilots holding active airplane license

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Palo Alto Health Care System

Palo Alto, California, 94304, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

saliva

MeSH Terms

Conditions

Memory Disorders

Condition Hierarchy (Ancestors)

Neurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jerome A Yesavage

    Stanford University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 31, 2011

First Posted

June 2, 2011

Study Start

January 1, 2006

Primary Completion

June 1, 2014

Study Completion

December 1, 2014

Last Updated

December 6, 2016

Record last verified: 2016-12

Locations

US(1)