The Effect of 1 Year of Multiprofessional Therapy on Obesity
Multiprofessional Impact on Body Composition, Central and Peripheric Adiposity, Lipid Profile, Hormonal Regulation, Lung, Sleep and Humor Disorders in Adolescents
1 other identifier
interventional
150
1 country
1
Brief Summary
Obese adolescents are submitted to a multiprofessional weight loss program, which is formed by doctors, nutritionists, physiotherapists, psychologists,and physiologists. The volunteers have intervention 3 times a week during one year, where they practice exercises, have nutrition and psychology counseling, and physiotherapy orientation. Once a month they have an appointment with the doctor. The hypothesis of this study is that a multiprofessional therapy is able to improve anthropometric and biochemical parameters, and also the quality of life of obese adolescents.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for early_phase_1 obesity
Started Feb 2004
Longer than P75 for early_phase_1 obesity
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2004
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2004
CompletedFirst Submitted
Initial submission to the registry
December 3, 2010
CompletedFirst Posted
Study publicly available on registry
May 24, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2016
CompletedJune 30, 2016
June 1, 2016
10 months
December 3, 2010
June 29, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Body composition
The body composition was measured by plethysmography and by densitometry.
six months
Secondary Outcomes (5)
visceral and subcutaneous fat were analyzed by ultrasound
six months
Serum analysis
six months
Lung function
six months
Arterial intima-media thickness
six months
Sleep parameters
six months
Study Arms (1)
Lifestyle counseling
OTHERObese adolescents are encouraged to improve their lifestyle
Interventions
Comparison of the polysomnography results, blood collection parameters, resting metabolic rate values, body composition variables, carotid artery thickness values, abdominal and subcutaneous fat and lung function variables baseline, middle and at the end of the one year of interdisciplinary weight loss program combined exercise training with physiotherapy, clinical, nutritional and psychological therapies.
Eligibility Criteria
You may qualify if:
- present obesity ( BMI \> 95th)
- aged between 15-19 years old
- be able to practice exercise
You may not qualify if:
- pregnancy
- use of drugs
- secondary obesity
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Ana R. Damasolead
- Raquel Munhoz da Silveira Camposcollaborator
- Sofia Emanuelle Castrocollaborator
- Ana Claudia Pelissari Kravchychyncollaborator
Study Sites (1)
CEPE
São Paulo, São Paulo, 04023-900, Brazil
Related Publications (5)
Roche J, Corgosinho FC, Damaso AR, Isacco L, Miguet M, Fillon A, Guyon A, Moreira GA, Pradella-Hallinan M, Tufik S, Tulio de Mello M, Gillet V, Pereira B, Duclos M, Boirie Y, Masurier J, Franco P, Thivel D, Mougin F. Sleep-disordered breathing in adolescents with obesity: When does it start to affect cardiometabolic health? Nutr Metab Cardiovasc Dis. 2020 Apr 12;30(4):683-693. doi: 10.1016/j.numecd.2019.12.003. Epub 2019 Dec 16.
PMID: 32008915DERIVEDMasquio DC, de Piano A, Campos RM, Sanches PL, Carnier J, Corgosinho FC, Netto BD, Carvalho-Ferreira JP, Oyama LM, Oller do Nascimento CM, Tock L, de Mello MT, Tufik S, Damaso AR. Reduction in saturated fat intake improves cardiovascular risks in obese adolescents during interdisciplinary therapy. Int J Clin Pract. 2015 May;69(5):560-70. doi: 10.1111/ijcp.12573. Epub 2014 Oct 9.
PMID: 25296762DERIVEDGrotti Clemente AP, Molin Netto BD, Ganen Ad, Tock L, Arisa Caranti D, de Mello MT, Tufik S, Damaso AR. Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents. J Nutr Metab. 2013;2013:724781. doi: 10.1155/2013/724781. Epub 2013 Dec 7.
PMID: 24381750DERIVEDde Piano A, de Mello MT, Sanches Pde L, da Silva PL, Campos RM, Carnier J, Corgosinho F, Foschini D, Masquio DL, Tock L, Oyama LM, do Nascimento CM, Tufik S, Damaso AR. Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents. Eur J Gastroenterol Hepatol. 2012 Nov;24(11):1313-24. doi: 10.1097/MEG.0b013e32835793ac.
PMID: 22932160DERIVEDCorgosinho FC, de Piano A, Sanches PL, Campos RM, Silva PL, Carnier J, Oyama LM, Tock L, Tufik S, de Mello MT, Damaso AR. The role of PAI-1 and adiponectin on the inflammatory state and energy balance in obese adolescents with metabolic syndrome. Inflammation. 2012 Jun;35(3):944-51. doi: 10.1007/s10753-011-9397-2.
PMID: 22038064DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ana R Dâmaso, PhD
Universidade Federal de São Paulo- UNIFESP - Escola Paulista de Medicina - EPM
Study Design
- Study Type
- interventional
- Phase
- early phase 1
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Associated Professor
Study Record Dates
First Submitted
December 3, 2010
First Posted
May 24, 2011
Study Start
February 1, 2004
Primary Completion
December 1, 2004
Study Completion
December 1, 2016
Last Updated
June 30, 2016
Record last verified: 2016-06