Admission Bio-clinical Score to Predict One-year Outcomes in Coiled Subarachnoid Hemorrhage (SAH)
ABCSAH
Biological Markers in Patients Presenting Aneurism Coiling for Subarachnoid Hemorrhage
1 other identifier
observational
530
1 country
1
Brief Summary
The goal of this observational study is to develop and validate a predictive score of 1-year outcomes in subarachnoid hemorrhage (SAH) patients receiving aneurism coiling. Using our database filled up prospectively, the investigators plan to collect clinical, biological and radiological admission characteristics of coiled SAH cases and their 1-year Rankin outcome score during 5 years (2003-2007). The investigators plan to confirm our score in a validation cohort (from 2008 to 2009).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2003
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2003
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2011
CompletedFirst Submitted
Initial submission to the registry
May 16, 2011
CompletedFirst Posted
Study publicly available on registry
May 20, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2011
CompletedDecember 29, 2011
May 1, 2011
8 years
May 16, 2011
December 27, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mortality and Full recovery (Rankin 0-1) at ICU discharge
at 1-year
Secondary Outcomes (2)
Early cerebral complication
Within the first week of ICU stay
Delayed cerebral complication
for the duration of hospital stay, an expected average of 3 weeks with an expected maximum of 3 months
Study Arms (2)
Derivation cohort
Arm 1: Derivation cohort (from 2003 to 2007)
Validation cohort
Arm 2: Validation cohort (from 2008 to 2009)
Eligibility Criteria
Adult coiled SAH after ICU admission
You may qualify if:
- Older than 18 years old
- Acute aneurysmal subarachnoid hemorrhage
- Decision of coiling intervention
- Admission and ICU management in our center.
You may not qualify if:
- Other intervention than coiling (surgery of nor surgery, nor coiling intervention)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Neuro-réanimation Chirurgicale Babinski - Hopital Pitié Salpetriere
Paris, 75013, France
Related Publications (1)
Degos V, Apfel CC, Sanchez P, Colonne C, Renuit I, Clarencon F, Nouet A, Boch AL, Pourmohamad T, Kim H, Gourraud PA, Young WL, Puybasset L. An admission bioclinical score to predict 1-year outcomes in patients undergoing aneurysm coiling. Stroke. 2012 May;43(5):1253-9. doi: 10.1161/STROKEAHA.111.638197. Epub 2012 Feb 23.
PMID: 22363051DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Louis Puybasset, MD, PhD
Assistance Publique - Hôpitaux de Paris
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 16, 2011
First Posted
May 20, 2011
Study Start
January 1, 2003
Primary Completion
January 1, 2011
Study Completion
September 1, 2011
Last Updated
December 29, 2011
Record last verified: 2011-05