NCT01356797

Brief Summary

Background: Selective unilateral spinal anesthesia is the gold standard spinal anesthesia technique for knee arthroscopy. Selective sensory spinal anesthesia has recently been validated for this surgery. Both selective techniques are specially indicated for ambulatory surgery because of PACU fast track, low discharge home time and high patient satisfaction. This study compares both spinal techniques for knee arthroscopy surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for phase_4 pain

Timeline
Completed

Started May 2011

Shorter than P25 for phase_4 pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2011

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

May 10, 2011

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 19, 2011

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2011

Completed
Last Updated

September 9, 2011

Status Verified

September 1, 2011

Enrollment Period

4 months

First QC Date

May 10, 2011

Last Update Submit

September 7, 2011

Conditions

Keywords

knee arthroscopyhyperbaric bupivacainehypobaric levobupivacaine plus fentanyl

Outcome Measures

Primary Outcomes (1)

  • time to discharge home

    In Day Surgery Unit, patients will be assessed for home discharge every 30 minutes and will be followed an expected average of three hours.

    every 30 minutes for an average of 3 hours

Secondary Outcomes (1)

  • Ambulation time after surgery

    every 30 minutes for an average of 3 hours

Study Arms (2)

hyperbaric bupivacaine

ACTIVE COMPARATOR
Drug: hyperbaric bupivacaine 0,5%

hypobaric levobupivacaine with fentanyl

EXPERIMENTAL
Drug: hypobaric levobupivacaine with fentanyl

Interventions

SSSA with 4 mg hypobaric levobupivacaine 0,13% with 10 mcg fentanyl

Also known as: Chirocane
hypobaric levobupivacaine with fentanyl

SUSA with 4 mg hyperbaric bupivacaine 0.5%

Also known as: Marchaine
hyperbaric bupivacaine

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adults scheduled to undergo knee arthroscopy

You may not qualify if:

  • a previous history of neurological impairment
  • insulin-dependent diabetes mellitus
  • intolerance to the study drug or related compounds and additives
  • BMI \> 38 kg/m2
  • height \<155 cm or \>180 cm
  • any existing contraindications for spinal anaesthesia
  • surgery in which a complete block of the lower limb

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital La Colina

Santa Cruz de Tenerife, Santa Cruz, 38007, Spain

Location

MeSH Terms

Conditions

Pain

Interventions

Fentanyl

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

PiperidinesHeterocyclic Compounds, 1-RingHeterocyclic Compounds

Study Officials

  • Jesus Santiago Moragas

    USP La Colina

    PRINCIPAL INVESTIGATOR
  • Javier Santos-Yglesias

    Department of Anesthesiology, Hospital La colina

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

May 10, 2011

First Posted

May 19, 2011

Study Start

May 1, 2011

Primary Completion

September 1, 2011

Study Completion

September 1, 2011

Last Updated

September 9, 2011

Record last verified: 2011-09

Locations