NCT01351402

Brief Summary

This study will investigate the effects of 15 minutes of massage compared to 15 minutes of quiet rest on physiological variables. Specifically, the investigators will measure the effects on levels of the social hormone oxytocin, and on other physiological variables that interact with oxytocin or that may be influenced by massage (including ACTH, Beta-endorphin, and IL-1alpha). The investigators will also investigate whether, in the case of hormones changes, these influence social decision making.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
95

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2006

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2006

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2006

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2007

Completed
4.3 years until next milestone

First Submitted

Initial submission to the registry

May 6, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 10, 2011

Completed
Last Updated

May 10, 2011

Status Verified

August 1, 2005

Enrollment Period

2 months

First QC Date

May 6, 2011

Last Update Submit

May 9, 2011

Conditions

MassageRest

Keywords

MassageRest

Outcome Measures

Primary Outcomes (1)

  • Oxytocin

    Participants receive a blood draw at baseline and immediately following 15 minutes of massage or rest and oxytocin will be measured from this sample.

    Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.

Secondary Outcomes (3)

  • Adrenocorticotrophic hormone (ACTH)

    Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.

  • Beta-endorphin

    Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.

  • Interleukin-1alpha (IL-1a)

    Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.

Interventions

Massage or RestPROCEDURE

Participants either received 15 minutes of moderate pressure Swedish massage on the upper back, or rested quietly sitting in a chair for 15 minutes.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Anyone English speaking and over the age of 18.

You may not qualify if:

  • Minors and anyone who has used illicit drugs or alcohol in the last 24 hours.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cassel, UCLA

Los Angeles, California, 90095, United States

Location

MeSH Terms

Interventions

MassageRE1-silencing transcription factor

Intervention Hierarchy (Ancestors)

Therapy, Soft TissueMusculoskeletal ManipulationsComplementary TherapiesTherapeuticsPhysical Therapy ModalitiesRehabilitation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
BASIC SCIENCE
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 6, 2011

First Posted

May 10, 2011

Study Start

June 1, 2006

Primary Completion

August 1, 2006

Study Completion

January 1, 2007

Last Updated

May 10, 2011

Record last verified: 2005-08

Locations

US(1)