Effects of Milk Derived From Mountain-pasture Grazing Cows on Risk Markers of the Metabolic Syndrome Compared to Conventional Danish Milk
1 other identifier
interventional
38
1 country
1
Brief Summary
To investigate the effect of milk delivered from mountain-pasture grazing cows on risk markers of the metabolic syndrome and type-2 diabetes with the effect of conventional Danish milk. The study should reveal the importance of phytanic acid content for these effects.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2010
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2010
CompletedFirst Submitted
Initial submission to the registry
April 18, 2011
CompletedFirst Posted
Study publicly available on registry
April 28, 2011
CompletedApril 28, 2011
June 1, 2010
5 months
April 18, 2011
April 27, 2011
Conditions
Outcome Measures
Primary Outcomes (7)
Oral glucose tolerance test
before and after the intervention (12 weeks)
LDL cholesterol
before and after the intervention (12 weeks)
HDL cholesterol
before and after the intervention (12 weeks)
Total cholesterol
before and after the intervention (12 weeks)
Triacylglycerol
before and after the intervention (12 weeks)
C-reactive protein
before and after the intervention (12 weeks)
fatty acid composition in plasma
before and after the intervention (12 weeks)
Secondary Outcomes (1)
phytanic acid
before and after the intervention (12 weeks)
Interventions
Eligibility Criteria
You may qualify if:
- sign written consent
- Age: 50-70
- BMI: 20-30
- increased risk of developing MS
- refrain from dietary supplements and blood donations prior to, and during the study
You may not qualify if:
- poor compliance
- if they suffering from any chronic or long lasting illness
- abuse of alcohol or medicine
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Copenhagenlead
- The Danish Dairy Research Foundation, Denmarkcollaborator
- The Danish Council for Strategic Researchcollaborator
Study Sites (1)
Department of Human Nutrition
Frederiksberg, 1958, Denmark
Related Publications (1)
Werner LB, Hellgren LI, Raff M, Jensen SK, Petersen RA, Drachmann T, Tholstrup T. Effects of butter from mountain-pasture grazing cows on risk markers of the metabolic syndrome compared with conventional Danish butter: a randomized controlled study. Lipids Health Dis. 2013 Jul 10;12:99. doi: 10.1186/1476-511X-12-99.
PMID: 23842081DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Tine Tholstrup, lector
Department of Human Nutrition, University of Copenhagen
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
April 18, 2011
First Posted
April 28, 2011
Study Start
January 1, 2010
Primary Completion
June 1, 2010
Study Completion
June 1, 2010
Last Updated
April 28, 2011
Record last verified: 2010-06