Relationship Between Gestational Diabetes and Type 2 Diabetes
GDM
Key Determinants of Type 2 Diabetes Prevention Among Women With a History of Gestational Diabetes Mellitus
1 other identifier
observational
450
1 country
1
Brief Summary
The overall objective of this research project is to study the impact of preventive practices on the T2D-related risk profile among women with and without prior GDM and their children exposed and unexposed to GDM.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2009
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2009
CompletedFirst Submitted
Initial submission to the registry
March 15, 2011
CompletedFirst Posted
Study publicly available on registry
April 25, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2023
CompletedApril 8, 2022
April 1, 2022
7 years
March 15, 2011
April 7, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Glucose tolerance assessed using a 75g-Oral Glucose Tolerance Test (OGTT) in mothers
1 year
Secondary Outcomes (7)
Glycaemic and lipidic profile assessed using a fasting blood sample in children
1 year
overweight/obesity
1 year
abdominal obesity
1 year
metabolic syndrome
1 year
Breastfeeding
1 year
- +2 more secondary outcomes
Eligibility Criteria
In order to avoid selection biases, we plan to recruit 450 women with a history of GDM through administrative data from the Régie de l'assurance maladie du Québec (RAMQ) and children of those mothers. We plan to recruit 125 women without history of GDM through mail sent to students and employees of local university and children of those mothers.
You may qualify if:
- Women aged ≥18 years with or without a diagnosis of GDM in the past 3-12 years and their children.
You may not qualify if:
- Pregnant women, women with type 1 diabetes.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Laval Universitylead
Study Sites (1)
Laval University, Institute of Nutraceuticals and Functional Foods
Québec, G1V 0A6, Canada
Related Publications (1)
Kearney M, Perron J, Marc I, Weisnagel SJ, Tchernof A, Robitaille J. Association of prenatal exposure to gestational diabetes with offspring body composition and regional body fat distribution. Clin Obes. 2018 Apr;8(2):81-87. doi: 10.1111/cob.12237. Epub 2017 Dec 13.
PMID: 29239129DERIVED
Biospecimen
whole blood; serum; white cell.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Julie Robitaille, R.D., Ph.D.
Laval University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
March 15, 2011
First Posted
April 25, 2011
Study Start
September 1, 2009
Primary Completion
September 1, 2016
Study Completion
December 1, 2023
Last Updated
April 8, 2022
Record last verified: 2022-04
Data Sharing
- IPD Sharing
- Will share