High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)

NCT01328340 | Completed

• 1 other identifier: 1043138
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

We are exploring a unique weight-training program for men and women 55 years or older with knee osteoarthritis (OA) that emphasizes high-speed movements. We believe that the speed at which muscles move may be more important to the improvement of muscle performance, function and pain than how strong the muscles are. We are comparing high-speed power training with traditional strength training to determine which method has the greatest effects on muscle strength, muscle power, speed of movement, functional performance and pain. We believe that high-speed training will improve these measures to a greater extent than simply training for increased muscle strength.

Conditions

Knee Osteoarthritis

Keywords

muscle power, exercise, aging

Outcome Measures

Primary Outcomes (1)

• Strength and power

  The strength of the lower limb muscles will be measures using Keiser pneumatic leg press and knee extension exercise machines. The Keiser machines allow for the specific measurement of the contributions of force and velocity to the development of power, which will reveal whether the high-speed training protocol impacts speed-related measures of muscle performance.

  3 months

Secondary Outcomes (1)

• Function

  3 months

Study Arms (3)

High-speed power training

ACTIVE COMPARATOR

Volunteers randomized into SHPT will be exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 12 to 14 repetitions at 40% of maximal strength for leg press (LP) and seated knee extension (KE) exercises.

Other: High-speed power training

Slow-speed strength training

ACTIVE COMPARATOR

Volunteers randomized into STR will be exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 8 to 10 repetitions at 80% of maximal strength for LP and KE exercises.

Other: Slow-speed strength training

Control

NO INTERVENTION

Volunteers randomized into CON will undergo a placebo exercise intervention consisting of lower extremity range of motion and flexibility exercises performed 2 times per week with the assistance of the research staff.

Interventions

High-speed power training OTHER

exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 12 to 14 repetitions at 40% of maximal strength

Also known as: weight training

High-speed power training

Slow-speed strength training OTHER

exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 8 to 10 repetitions at 80% of maximal strength

Also known as: weight training

Slow-speed strength training

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years of age
• physician diagnosed knee OA
• relatively inactive
• male or female
• good overall health
• living independently (not in a nursing home or care facility)

You may not qualify if:

• heart attack or unstable angina within 6 months of consent
• hip fracture, knee or hip replacement within 6 months of consent
• diagnosed neurological disease
• pulmonary disease requiring use of oxygen
• osteoarthritis of the knee
• severe visual or hearing impairment

Sponsors & Collaborators

• University of Missouri-Columbia: lead
• American College of Rheumatology: collaborator
• Arthritis Foundation: collaborator

Study Sites (1)

University of Missouri

Columbia, Missouri, 65211, United States

Location

Related Publications (1)

• Sayers SP, Gibson K, Cook CR. Effect of high-speed power training on muscle performance, function, and pain in older adults with knee osteoarthritis: a pilot investigation. Arthritis Care Res (Hoboken). 2012 Jan;64(1):46-53. doi: 10.1002/acr.20675.

  PMID: 22012877 DERIVED

MeSH Terms

Conditions

Osteoarthritis, Knee; Motor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Stephen P Sayers, PhD

  University of Missouri-Columbia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 31, 2011
• First Posted: April 4, 2011
• Study Start: June 1, 2005
• Primary Completion: May 1, 2008
• Study Completion: May 1, 2008
• Last Updated: October 4, 2016

Record last verified: 2016-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)