NCT00904319

Brief Summary

Knee Osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults. The purpose of this research is to reduce disablement of older adults with symptomatic knee osteoarthritis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
81

participants targeted

Target at P50-P75 for not_applicable knee-osteoarthritis

Timeline
Completed

Started Apr 2009

Shorter than P25 for not_applicable knee-osteoarthritis

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2009

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

May 15, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 19, 2009

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

June 25, 2010

Status Verified

June 1, 2010

Enrollment Period

8 months

First QC Date

May 15, 2009

Last Update Submit

June 24, 2010

Conditions

Knee Osteoarthritis

Keywords

osteoarthritisknee painpower trainingrehabilitation

Outcome Measures

Primary Outcomes (1)

  • 400 meter walk time

    0, 6, and 12 weeks

Secondary Outcomes (4)

  • Lower limb function (LLFDI)

    0, 6, and 12 weeks

  • Quality of life (KOOS)

    0, 6, and 12 weeks

  • Knee osteoarthritis pain (KOOS pain scores)

    0 and 6 weeks

  • Vastus lateralis muscle bulk

    0, 2, 6, and 12 weeks

Study Arms (1)

Aquatic

EXPERIMENTAL

Aquatic Power Training

Other: Aquatic Power Training

Interventions

Aquatic Power TrainingOTHER

Aquatic power training program with an exercise specialist 2/week for 6 weeks.

Aquatic

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 50 or older
  • Symptomatic knee osteoarthritis (knee osteoarthritis diagnosed by the American College of Rheumatology criteria and frequent knee symptoms)

You may not qualify if:

  • bilateral knee replacement
  • acute or terminal illness
  • unstable cardiovascular condition or other medical conditions that may impair ability to participate such as pulmonary disease requiring use of supplement oxygen, or lower limb musculoskeletal surgery in the past 6 months
  • unwilling to be in a pool (approximately 4 feet deep)
  • m walk time equal to or slower than the median for sex and decade:
  • M 50's 250.2 60's 289.9 70's+ 290.8
  • F 50's 315.9 60's 305.2 70's+ 292.5

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Iowa

Iowa City, Iowa, 52242, United States

Location

MeSH Terms

Conditions

Osteoarthritis, KneeOsteoarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Neil A Segal, MD, MS

    University of Iowa

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 15, 2009

First Posted

May 19, 2009

Study Start

April 1, 2009

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

June 25, 2010

Record last verified: 2010-06

Locations

US(1)