Effect of Speed-dependent Treadmill Training in Patients With Subacute Stroke

NCT01328301 | Completed DMC

• 1 other identifier: mak0001
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to explore whether speed-dependent treadmill training is more effective at improving walking and balance performance than speed-stable treadmill training in patients with subacute stroke. Twenty-six patients with stroke completed 2 weeks of treadmill training. Results showed that speed-dependent treadmill training is more effective at improving walking speed and step length than speed-stable treadmill training in patients with subacute stroke.

Conditions

Stroke

Keywords

gait; hemiplegia; treadmill; physiotherapy; rehabilitation

Outcome Measures

Primary Outcomes (3)

• change in Walking speed

  Change in walking speed from baseline to post-treatment, an expected average of 2 weeks

• change in stride length

  Change in stride length from baseline to post-treatment, an expected average of 2 weeks

• change in cadence

  Change in cadence from baseline to post-treatment, an expected average of 2 weeks

Secondary Outcomes (1)

• change in Berg's balance score

  Change in Berg's balance score from baseline to post-treatment, an expected average of 2 weeks

Study Arms (2)

Speed-dependent treadmill training (SDT)

EXPERIMENTAL

Subjects underwent short interval of walking trials with stepwise increases in the treadmill speed

Other: Experimental

speed-stable treadmill training

ACTIVE COMPARATOR

Control subjects received gait training on the treadmill with a steady speed.

Other: Speed-stable treadmill training

Interventions

Experimental OTHER

For SDT training, subjects received short intervals of locomotion training with a treadmill. After walking for 30s, the subjects were given two minutes of rest. If they completed the first walking trial safely and without stumbling, the belt speed was increased by 10% on the next trial. However, if a subject failed to complete the first trial, the belt speed was decreased by 10% on the next trial. The speed of the treadmill was adjusted in each subsequent trial according to the same principle. Subjects usually completed 7-8 walking trials in one session. The belt speed was increased by a maximum of five increments within one training session.

Also known as: Treadmill training with increasing speed

Speed-dependent treadmill training (SDT)

Speed-stable treadmill training OTHER

Subjects in the control group walked on the treadmill with the belt speed adjusted according to their fastest over-ground gait speed. There was no adjustment of the belt speed throughout the 30-minute steady-speed treadmill training session.

Also known as: Treadmill training with steady speed

speed-stable treadmill training

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• first episode of stroke
• within 1 month of stroke onset
• hemiparesis resulting from unilateral ischemic stroke
• Ashworth score of 0 or 1 indicating no spasticity or slight spasticity over the affected lower limb respectively
• mini-mental status examination score of ≥ 23
• the ability to walk on level ground without physical assistance and to walk on a treadmill with a minimum speed of 22.2 cm/s for 30s

You may not qualify if:

• neurological diseases other than stroke,
• active cardiovascular disease (i.e. American Heart Association class C or above),
• lower limb fractures
• total hip replacement
• active rheumatoid arthritis that affected their gait performance
• Patients who required assistance to ambulate before the stroke were also excluded

Sponsors & Collaborators

• The Hong Kong Polytechnic University: lead
• Tung Wah Hospital: collaborator

Study Sites (1)

Margaret Mak

Hong Kong, Hong Kong, China

Location

MeSH Terms

Conditions

Stroke; Hemiplegia

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Margaret KY Mak, PhD

  Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: March 31, 2011
• First Posted: April 4, 2011
• Study Start: December 1, 2008
• Primary Completion: December 1, 2009
• Study Completion: December 1, 2009
• Last Updated: March 20, 2015

Record last verified: 2015-03

Locations

CN (1)