NCT01327898

Brief Summary

The specific aims of the 5-year study are to: 1) describe the nature and extent of substance use and sexual risk behaviors in a sample of 500 sexually active, substance using, not-in-treatment men who have sex with men (MSM) in urban South Florida (Miami/Ft. Lauderdale); 2) identify the independent covariates of baseline substance abuse and sexual risks; 3) evaluate, through random assignment of participants, the relative effectiveness of two intervention conditions in reducing sexual risks and substance use, as measured at 3-, 6-, and 12-month follow-up assessments: a) an innovative five-session risk reduction intervention derived from psychological empowerment theory titled Project GOAL; and, b) an enhanced community standard-of-care HIV counseling Comparison Condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
515

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Nov 2008

Longer than P75 for phase_2

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

March 30, 2011

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 4, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
2.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
Last Updated

July 25, 2014

Status Verified

July 1, 2014

Enrollment Period

3.1 years

First QC Date

March 30, 2011

Last Update Submit

July 24, 2014

Conditions

Keywords

MSMHIV/AIDSsexual risksubstance use

Outcome Measures

Primary Outcomes (3)

  • unprotected anal intercourse events outside of primary relationships

    3 months

  • unprotected anal intercourse events outside of primary relationships

    6 months

  • unprotected anal intercourse events outside of primary relationships

    12 months

Study Arms (2)

1

EXPERIMENTAL

empowerment theory-based small group discussion

Behavioral: empowerment theory-based small group discussion

2

ACTIVE COMPARATOR

single session individual resilience counseling

Behavioral: individual resilience counseling

Interventions

four small group discussion sessions followed by one individual counseling session

1

one individual resilience counseling session

2

Eligibility Criteria

Age18 Years - 55 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • ongoing substance use and ongoing unprotected anal intercourse with men

You may not qualify if:

  • past twelve month participation in HIV prevention intervention or drug treatment; no current working telephone number and residential address; no intention to remain in in South Florida for next 12 months; newly diagnosed with HIV infection in the past 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

NSU Research Center

Miami Beach, Florida, 33139, United States

Location

NSU Research Center

Wilton Manors, Florida, 33305, United States

Location

MeSH Terms

Conditions

HIV InfectionsSubstance-Related DisordersAcquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesChemically-Induced DisordersMental DisordersSlow Virus Diseases

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 30, 2011

First Posted

April 4, 2011

Study Start

November 1, 2008

Primary Completion

December 1, 2011

Study Completion

July 1, 2014

Last Updated

July 25, 2014

Record last verified: 2014-07

Locations