NCT00375102

Brief Summary

This one-year pilot study has two specific aims: 1. to determine the feasibility of conducting a randomized controlled trial of acupuncture and the relaxation response for substance abuse among homeless veterans who are in a domiciliary care program, and 2. to collect and analyze pilot data to estimate the effect size for planning a future larger study to fully test the hypothesis of the effectiveness of acupuncture and the RR in reducing cravings for substances (alcohol and drugs), and the corollary effects on quality of life.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
67

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Nov 2006

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 11, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 12, 2006

Completed
2 months until next milestone

Study Start

First participant enrolled

November 1, 2006

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2007

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2007

Completed
Last Updated

December 15, 2014

Status Verified

December 1, 2014

Enrollment Period

10 months

First QC Date

September 11, 2006

Last Update Submit

December 12, 2014

Conditions

Keywords

acupuncturerelaxation responsehomelessveteransrandomized trials

Outcome Measures

Primary Outcomes (1)

  • Changes in self-reported substance craving rating from baseline to 10 week

    baseline and 10 week follow up

Secondary Outcomes (2)

  • Changes in anxiety level from baseline to 10 week

    baseline and 10 week follow up

  • Changes in quality of life from baseline to 10 week

    baseline and 10 week follow up

Study Arms (3)

Acup

EXPERIMENTAL

Acupuncture

Procedure: Acupuncture

RR

EXPERIMENTAL

Relaxation Response

Behavioral: Relaxation Response

UC

NO INTERVENTION

Usual Care

Interventions

AcupuncturePROCEDURE
Acup

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have a substance abuse or dependence problem of any type of substance
  • Stay in the domiciliary for at least 10 weeks after the study entry to complete the study.

You may not qualify if:

  • Schizophrenia or psychotic diagnoses
  • Bleeding disorders (hemophilia or thrombocytopenia)
  • An allergy to metals (needles).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bedford VAMC

Bedford, Massachusetts, 01730, United States

Location

Related Publications (2)

  • Chang BH, Sommers E. Acupuncture and relaxation response for craving and anxiety reduction among military veterans in recovery from substance use disorder. Am J Addict. 2014 Mar-Apr;23(2):129-36. doi: 10.1111/j.1521-0391.2013.12079.x. Epub 2013 Aug 30.

  • Chang BH, Elizabeth Sommers, Lawrence Herz, Acupuncture and relaxation response for substance use disorder recovery, Journal of Substance Use, 2010, 15(6): 390-401.

    RESULT

MeSH Terms

Conditions

Substance-Related Disorders

Interventions

Acupuncture Therapy

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeutics

Study Officials

  • Bei-Hung Chang, Sc.D.

    VA Boston Health Care System

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Health Research Scientist

Study Record Dates

First Submitted

September 11, 2006

First Posted

September 12, 2006

Study Start

November 1, 2006

Primary Completion

September 1, 2007

Study Completion

November 1, 2007

Last Updated

December 15, 2014

Record last verified: 2014-12

Locations