Cognitive and Emotional Processing of Social Stimuli in Children and Youth With Autism Spectrum Disorder
1 other identifier
interventional
60
1 country
1
Brief Summary
Children and youth diagnosed with autism spectrum disorder (ASD) have been shown to react abnormally to social stimuli, especially to human faces. Children and youth with ASD show less interest in social stimuli, and may even avoid looking at or interact with such stimuli. It has been proposed that social stimuli elicit reactions like fear and stress in individuals with ASD, and this explains the lack of interest and avoidance. The present project investigates this hypothesis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2011
CompletedFirst Submitted
Initial submission to the registry
March 2, 2011
CompletedFirst Posted
Study publicly available on registry
March 25, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2013
CompletedOctober 25, 2012
October 1, 2012
1.8 years
March 2, 2011
October 24, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The eyeblink of the Startle reflex is measured.
The startle reflex is potentiated when participants are influenced by negative emotions. Accordingly, startle will be measured in relation to picture presentation to gauge the emotional effect of the pictures. It is expected that the ASD group will show fear potentiated startle to pictures of human faces.
The startle reflex will be measured in relation to picture presentations during the experiment (e.g. day 1).
Study Arms (2)
Normal controls
ACTIVE COMPARATORNormal children and youths
ASD
EXPERIMENTALChildren and youths diagnosed with autism spectrum disorder (ASD)
Interventions
The participants will be exposed to pictures of faces and non-facial stimuli presented on a PC screen.
Startle will be elicited by 95 dB noise, presented at different times after picture onset.
Eligibility Criteria
You may qualify if:
- Diagnosed with autism spectrum disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Tromsolead
- The Royal Norwegian Ministry of Healthcollaborator
Study Sites (1)
Department of Psychology, University of Tromso
Tromsø, Troms, 9037, Norway
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 2, 2011
First Posted
March 25, 2011
Study Start
March 1, 2011
Primary Completion
January 1, 2013
Last Updated
October 25, 2012
Record last verified: 2012-10