NCT01316562

Brief Summary

The purpose of this study is to determine the predictive value of standardized cognitive tests performed in health examination centres for the diagnosis of Alzheimer's disease and related disorders among adults aged 65 years and older with a subjective memory complaint.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2009

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2009

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

March 11, 2011

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 16, 2011

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2012

Completed
Last Updated

March 9, 2012

Status Verified

March 1, 2011

Enrollment Period

2 years

First QC Date

March 11, 2011

Last Update Submit

March 8, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Score of episodic memory and executive psychometric tests

    Baseline

Study Arms (2)

Group 1

Healthy controls

Group 2

Patients with an Alzheimer's disease or related disorders

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

All subjects with memory complaint recruited during a free medical examination in Health examination centres of Lyon, Saint-Etienne and Angers, France

You may qualify if:

  • Age ≥ 65 years
  • Community-dwellers
  • Volunteers receiving a free medical examination in Health examination centre
  • Subjective memory complaint

You may not qualify if:

  • Known dementia
  • Sensory deficit compromising the cognitive evaluation
  • Poor workmanship of the written or oral French language

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CES Baraban

Lyon, 69456, France

RECRUITING

Related Publications (2)

  • Vannier-Nitenberg C, Dauphinot V, Bongue B, Sass C, Bathsavanis A, Rouch I, Deville N, Beauchet O, Krolak-Salmon P, Fantino B. Performance of cognitive tests, individually and combined, for the detection of cognitive disorders amongst community-dwelling elderly people with memory complaints: the EVATEM study. Eur J Neurol. 2016 Mar;23(3):554-61. doi: 10.1111/ene.12888. Epub 2015 Oct 30.

  • Vannier-Nitenberg C, Dauphinot V, Bongue B, Sass C, Rouch I, Beauchet O, Krolak-Salmon P, Fantino B. Early detection of memory impairment in people over 65 years old consulting at Health Examination Centers for the French health insurance: the EVATEM protocol. BMC Geriatr. 2013 Jun 6;13:55. doi: 10.1186/1471-2318-13-55.

MeSH Terms

Conditions

Alzheimer DiseaseCognition DisordersMemory Disorders

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental DisordersNeurobehavioral ManifestationsNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Bruno Fantino, Professor

    CES de Baraban, Lyon

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Bruno Fantino, Professor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

March 11, 2011

First Posted

March 16, 2011

Study Start

July 1, 2009

Primary Completion

July 1, 2011

Study Completion

July 1, 2012

Last Updated

March 9, 2012

Record last verified: 2011-03

Locations