Effect of Whole-Body Vibration on Plasma Sclerostin Level
WBV-SCL
1 other identifier
interventional
15
1 country
1
Brief Summary
The aim of this study is to investigate effect of whole-body vibration on plasma sclerostin level in healthy young adult women. Fifteen healthy young adult women are planned to include in this study. All cases will be trained on a whole-body vibration (WBV) platform (Power Plate) 5 times a week for one week period. Training duration will be short at the beginning but progressed slowly. The amplitude of vibration will be 2 mm and the frequency of the vibration will be 40 Hz. The subjects will be asked to report negative side effects or adverse reactions in their training diary. Previbration and postvibration (just after, 10.minute and 30.minute) levels of plasma sclerostin will be measured on first, second and fifth day of experiment. Sclerostin levels will be measured by human sclerostin ELISA kit.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Apr 2011
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 7, 2011
CompletedFirst Posted
Study publicly available on registry
March 8, 2011
CompletedStudy Start
First participant enrolled
April 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2011
CompletedFebruary 25, 2016
February 1, 2016
Same day
March 7, 2011
February 23, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Plasma Sclerostin Level
Change of plasma sclerostin level with whole-body vibration
1 month
Study Arms (1)
Training
EXPERIMENTALThe whole-body vibration (WBV) training
Interventions
All cases will be trained on a whole-body vibration (WBV) platform (Power Plate) 5 times a week for one week period.
Eligibility Criteria
You may qualify if:
- Healthy women,
- Women with ages varying between 20 and 40 years
- Right-handed women
You may not qualify if:
- Lower extremity problems
- Orthopedic problems: shortness of legs, congenital anomalies, etc.
- Joint disease (arthritis, joint prosthesis, etc.)
- Other painful pathologies in the lower extremities (fractures, tendinitis,bursitis, etc.)
- Circulation problems in the lower extremities
- Dorsolumbar diseases: Vertebral fract, disc hernias, spondylodiskitis, etc.
- Systemic disease cases
- Systemic bone disease: osteoporosis, osteomalacia, Paget's disease
- Hypertension (\>135 mmHg systolic, \>85 mmHg diastolic)
- Heart dis.(coronary dis, conduction/rhythm prob, cardiac pacemaker)
- Infectious diseases
- Endocrine diseases (Diabetes mellitus etc)
- Neurological diseases (CNS problems, peripheral neuropathy)
- Menstrual cycle disorders, amenorrhea, lactation, oral contraceptive use
- Cases during the ovulatory period (11-16th day of menses)
- +5 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bagcilar Training & Research Hospital
Istanbul, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
ILHAN KARACAN, MD
Bagcilar Training & Research Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Chief of Physical Med & Rehab Clinic
Study Record Dates
First Submitted
March 7, 2011
First Posted
March 8, 2011
Study Start
April 1, 2011
Primary Completion
April 1, 2011
Study Completion
April 1, 2011
Last Updated
February 25, 2016
Record last verified: 2016-02
Data Sharing
- IPD Sharing
- Will not share