NCT01308476

Brief Summary

6 months open label non-interventional observational study acc to § 4, section 23 and § 67, section 6 German Medicines Act with two parallel groups

  1. 1.the SMS group receiving a daily SMS - a reminder to inhale Spiriva® 18 Microgram
  2. 2.the control group not receiving a daily SMS reminder

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
95

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 1, 2011

Completed
Same day until next milestone

Study Start

First participant enrolled

March 1, 2011

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 4, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

December 21, 2012

Completed
Last Updated

January 18, 2013

Status Verified

January 1, 2013

Enrollment Period

8 months

First QC Date

March 1, 2011

Results QC Date

November 20, 2012

Last Update Submit

January 17, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Adherence to Spiriva HandiHaler Over Time

    Adherence was defined as percentage of documented applications of Spiriva HandiHaler as compared to the regularly planned seven applications during the week before questioning the patients. Patients in the SMS reminder group and in the control group were asked via SMS how often they had used Spiriva HandiHaler during the last week and were requested to call the IVR system to provide their response. Baseline was defined as week 4.

    Baseline, Week 8, Week 12, Week 16, Week 20 and Week 24

Secondary Outcomes (7)

  • Change From Baseline in Adherence to Spiriva HandiHaler Over Time

    Week 8, Week 12, Week 16, Week 20 and Week 24

  • Response Rate Regarding Adherence

    24 weeks

  • Patients Compliance With SMS System

    24 weeks

  • Patients Assessment of Usefulness of the SMS System

    Visit 2 (12 weeks) and visit 3 (24 weeks)

  • Physicians Assessment of Usefulness of the SMS System

    Visit 2 (12 weeks) and visit 3 (24 weeks)

  • +2 more secondary outcomes

Study Arms (2)

SMS group

Procedure: SMS reminder

control group

Procedure: control group

Interventions

SMS reminderPROCEDURE

daily SMS in the SMS group to remind of treatment with tiotropium

SMS group
control groupPROCEDURE

no daily SMS to remind of treatment with tiotropium

control group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients

You may qualify if:

  • Chronic obstructive pulmonary disease (COPD) patients requiring long-acting bronchodilators according to approved Summary of Product Characteristics (SPC) and guidelines
  • User of mobile phone

You may not qualify if:

  • \- Patients presenting with the general and specific contraindications listed in the Patient Information Leaflet and the SPC

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Boehringer Ingelheim Investigational Site 1

Berlin, Germany

Location

Boehringer Ingelheim Investigational Site 2

Cottbus, Germany

Location

Boehringer Ingelheim Investigational Site 3

Hamburg, Germany

Location

Boehringer Ingelheim Investigational Site 4

Koblenz, Germany

Location

Boehringer Ingelheim Investigational Site 5

Lübeck, Germany

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Results Point of Contact

Title
Boehringer Ingelheim Call Center
Organization
Boehringer Ingelheim Pharmaceuticals

Study Officials

  • Boehringer Ingelheim

    Boehringer Ingelheim

    STUDY CHAIR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 1, 2011

First Posted

March 4, 2011

Study Start

March 1, 2011

Primary Completion

November 1, 2011

Last Updated

January 18, 2013

Results First Posted

December 21, 2012

Record last verified: 2013-01

Locations