NCT01308216

Brief Summary

The aim of this study is to determine the efficacy of transcranial laser therapy applied in automatic noncontact scanning mode for improving functional disability in patients with hemiplegia from ischemic stroke undergoing a rehabilitation program.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at P25-P50 for phase_1

Timeline
Completed

Started Nov 2010

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2010

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

March 3, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 4, 2011

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2011

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

April 3, 2012

Status Verified

November 1, 2011

Enrollment Period

10 months

First QC Date

March 3, 2011

Last Update Submit

April 2, 2012

Conditions

Keywords

Transcranial Laser TherapyHemiplegiaRehabilitationPhysiotherapyIschemic stroke

Outcome Measures

Primary Outcomes (1)

  • Fugl-Meyer Scale

    The upper extremity Fugl-Meyer subscale (0-66) considers flexor and extensor synegies as well as reflex activity and coordination and is specific for grading motor impairments.

    20 minutes

Secondary Outcomes (1)

  • Barthel index

    10 minutes

Study Arms (2)

Transcranial low level laser therapy

EXPERIMENTAL

Transcranial laser therapy is applied by automatic scanning over both hemispheres and the patients undergoing also a standard rehabilitation program based on therapeutic exercises.

Procedure: low level laser therapy procedure

Control

ACTIVE COMPARATOR

The patients undergoing only a standard rehabilitation program based on therapeutic exercises.

Procedure: low level laser therapy procedure

Interventions

Transcranial low level laser therapy by automatic scanning noncontact over both cerebral hemispheres.

Also known as: COMBY 3 Terza Serie C-LASER; ASA.
ControlTranscranial low level laser therapy

Eligibility Criteria

Age40 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with hemiplegia secondary to cerebral stroke ischemic.
  • Requirement of shaving the scalp area.
  • Initiation of the TLT procedure begins between 70 and 100 days after stroke onset.
  • Informed written consent before enrolling in the study.

You may not qualify if:

  • Hemiplegia secondary to hemorrhagic stroke.
  • Metallic brain implants.
  • Neurodegenerative disorders.
  • Bilateral motor problems.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Ramon y Cajal

Madrid, Madrid, 28034, Spain

Location

MeSH Terms

Conditions

HemiplegiaIschemic Stroke

Condition Hierarchy (Ancestors)

ParalysisNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsStrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Ramón Montes-Molina, PT

    Hospital University Ramon y Cajal. IRYCIS.Madrid

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physical Therapy

Study Record Dates

First Submitted

March 3, 2011

First Posted

March 4, 2011

Study Start

November 1, 2010

Primary Completion

September 1, 2011

Study Completion

December 1, 2011

Last Updated

April 3, 2012

Record last verified: 2011-11

Locations