NCT01307163

Brief Summary

Saliva is used nowadays as a significant diagnostic tool due to the latest technological developments. The research compares two experimental groups; children after liver transplantation and a control group. Our objective is to identify from all the parameters that are evaluated, the ones that differ between the two groups. If such parameters will be found and differ statistically, it will be possible to create a non invasive medical examination protocol, which will probably be much more complaint, and being so would help locate individuals in risk groups with the tendency to develop an end-organ liver disease.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

January 10, 2008

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
2.2 years until next milestone

First Posted

Study publicly available on registry

March 2, 2011

Completed
Last Updated

March 2, 2011

Status Verified

December 1, 2007

Enrollment Period

11 months

First QC Date

January 10, 2008

Last Update Submit

March 1, 2011

Conditions

Liver Transplant

Keywords

salivaliver transplantationchildrenIn this prospective study 60 subjects will be examinedchildren and adolescentsafter a successful liver transplantationinformed consent forms signed be the examinees parents

Eligibility Criteria

Age2 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

In this prospective study 60 subjects will be examined. Children and adolescents from Schnaidder's hospital for children after a successful liver transplantation will be characterized as the study group. As a control group, 32 healthy examinees in the same age group will be selected from the dental pediatric department at Hadassah hospital, Ein karem, Jerusalem

You may qualify if:

  • Children after a successful liver transplantation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah Medical Organization IRB

Jerusalem, 12000, Israel

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

saliva

Study Design

Study Type
observational
Observational Model
COHORT
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 10, 2008

First Posted

March 2, 2011

Study Start

January 1, 2008

Primary Completion

December 1, 2008

Study Completion

December 1, 2008

Last Updated

March 2, 2011

Record last verified: 2007-12

Locations

IL(1)