Contribution Of Nuclear Magnetic Resonance Imaging In The Study Of Diabetic Cardiomyopathy
2 other identifiers
interventional
25
1 country
1
Brief Summary
Diagnosis of diabetic cardiomyopathy is then retained, supposing a change in the coronary microcirculation linked to an endothelial dysfunction. Abnormalities of the myocardial metabolism is frequently associated. It is regrettably about a hypothesis difficult to verify with current medical techniques.This deficiency being not only harmful to the diagnosis, but also to the assessment of the efficiency of the medical treatment on the myocardial metabolism and the endothelial function. Techniques of nuclear magnetic resonance offer interesting perspectives.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2011
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 26, 2011
CompletedStudy Start
First participant enrolled
February 1, 2011
CompletedFirst Posted
Study publicly available on registry
February 14, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2015
CompletedApril 22, 2015
April 1, 2015
4.3 years
January 26, 2011
April 20, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
To quantify the myocardial blood flow at rest and after "cold pressor test" in a population of healthy volunteers
The myocardial blood flow will be obtained by estimating myocardial blood flow at the venous coronary sinus site. This allows us to quantify a possible endothelial dysfunction in a reproducible way. No MRI study in diabetic patients has ever been led until now with this technique.
12 months
Secondary Outcomes (1)
To estimate the metabolic and structural abnormalities in this population
12 months
Study Arms (2)
healthy volunteers
EXPERIMENTALpatients with a diabetic cardiomyopathy
ACTIVE COMPARATORInterventions
Techniques of nuclear magnetic resonance offer interesting perspectives in this context, and particularly to quantify the myocardial blood flow at rest and after "cold pressor test" in a population of healthy volunteers.
Eligibility Criteria
You may qualify if:
- more than 18 years old
- patient type 2 diabetes affects taken care more than 5 years to Timone Hospital
- patient with a diabetic cardiomyopathy
- informed and consented
You may not qualify if:
- less than 18 years
- Pregnant woman
- patient type 1 diabetes affects
- patient presents a cardiomyopathy mixed (no diabetic)
- patients presents an arrhythmia ventriculaire or above - ventriculaire
- Unstable hémodynamique patients
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assistance Publique - Hopitaux de Marseille
Marseille, 13, France
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jacques Quilici, Doctor
APHM
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 26, 2011
First Posted
February 14, 2011
Study Start
February 1, 2011
Primary Completion
June 1, 2015
Study Completion
June 1, 2015
Last Updated
April 22, 2015
Record last verified: 2015-04